The effects of a combination of piretanide and triamterene in healthy subjects.

Daneshmend, T K; Homeida, M.; Roberts, CJ; Dombey, SL

doi:10.1111/j.1365-2125.1981.tb01117.x

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Identification Of Distal Site Of Action1

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1981

1985

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“…Potassium excretion rates taken during peak natriuresis following administration of the first dose of the drug should be compared with control values. Subsequent repeated administration will result in a new state in which potassium excretion balances intake (Daneshmend et al, 1981).…”

Section: Identification Of Distal Site Of Actionmentioning

confidence: 99%

Assessment of natriuretic drugs.

Roberts¹,

Daneshmend²

1981

Brit J Clinical Pharma

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Section: Identification Of Distal Site Of Actionmentioning

confidence: 99%

Assessment of natriuretic drugs.

Roberts¹,

Daneshmend²

1981

Brit J Clinical Pharma

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Piretanide: A Loop‐Active Diuretic

Marsh

Smith

1984

Pharmacotherapy

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Piretanide is a high-ceiling, loop-active diuretic that has been developed for treatment of congestive heart failure, hypertension and edematous states caused by renal and hepatic diseases. Piretanide is structurally related to furosemide and bumetanide; when administered orally, 6 mg of piretanide is as effective as 40 mg of furosemide, and when administered intravenously, 12 mg of piretanide is as effective as 40 mg of furosemide. Piretanide enhances water and sodium excretion in patients with congestive heart failure, with nephrotic syndrome and with cirrhosis and ascites. Adverse effects reported to date are limited to those attributable to excess loss of fluid and electrolytes. Under some conditions, piretanide appears to be less potassium wasting than thiazide diuretics or other loop-active diuretics.

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Commentary 4

Vlasses

Larijani

1984

Pharmacotherapy

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The effects of a combination of piretanide and triamterene in healthy subjects.

Cited by 4 publications

References 9 publications

Assessment of natriuretic drugs.

Assessment of natriuretic drugs.

Piretanide: A Loop‐Active Diuretic

Commentary 4

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