The Effects of a Smoking Cessation Intervention on 14.5-Year Mortality

Anthonisen, Nicholas R.; Skeans, M. A.; Wise, Robert A.; Manfreda, Jure; Kanner, Richard E.; Connett, John E.

doi:10.7326/0003-4819-142-4-200502150-00005

Cited by 1,109 publications

(569 citation statements)

References 113 publications

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“…There is some evidence for a benefit of smoking cessation for specific causes of death in other populations. In the Lung Health study, which comprised individuals who were, on average, heavy smokers with evidence of airway obstruction, mortality rates fell progressively from those who continued to smoke, to intermittent quitters and to those who successfully stopped smoking 29. This pattern was seen for deaths due to coronary heart disease, CVD, and lung cancer (but not other forms of cancer).…”

Section: Discussionmentioning

confidence: 99%

Smoking‐Related Mortality in Patients With Early Rheumatoid Arthritis: A Retrospective Cohort Study Using the Clinical Practice Research Datalink

Joseph

Movahedi

Dixon

et al. 2016

Arthritis Care & Research

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ObjectiveTo investigate the association between smoking status and smoking cessation with mortality in patients with rheumatoid arthritis (RA).MethodsAn incident cohort of patients with RA was identified using the Clinical Practice Research Datalink, a database of UK primary care electronic medical records. Time‐varying smoking status, years of cessation, and amount smoked were determined from patients' medical records. The date and underlying cause of death were identified by linkage with Office for National Statistics records. The associations between smoking status and smoking cessation with all‐cause and cause‐specific mortality (circulatory disease, all cancers, lung cancer, respiratory disease, and respiratory infection) were investigated using adjusted Cox (all‐cause mortality) and Fine‐Gray (cause‐specific mortality) regression.ResultsThe cohort comprised 5,677 patients (median age 61.4 years, 68% women), with 40% as never smokers, 34% former smokers, and 26% current smokers at baseline. Compared to never smoking, current smoking was associated with an increased risk of all‐cause mortality (hazard ratio 1.98 [95% confidence interval (95% CI) 1.56, 2.53]), and mortality due to circulatory disease (subdistribution hazard ratio [SHR] 1.96 [95% CI 1.33, 2.90]) and lung cancer (SHR 23.2 [95% CI 5.15, 105]). Each year of smoking cessation was associated with a decreased risk of all‐cause mortality (former heavy smokers SHR 0.85 [95% CI 0.77, 0.94], former light smokers SHR 0.90 [95% CI 0.84, 0.97]).ConclusionCurrent smoking is associated with an increased risk of all‐cause, cardiovascular, and lung cancer mortality in patients with RA. Each year of cessation is associated with a reduced risk of all‐cause mortality. This information may prove helpful in smoking cessation programs for patients with RA.

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Section: Discussionmentioning

confidence: 99%

Smoking‐Related Mortality in Patients With Early Rheumatoid Arthritis: A Retrospective Cohort Study Using the Clinical Practice Research Datalink

Joseph

Movahedi

Dixon

et al. 2016

Arthritis Care & Research

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“…Elimination of risks (1 st step): Smoking cessation significantly decelerates the declination in lung function 4,5,56,57 . In contrast, it has been clearly demonstrated that continuing exposure to smoke considerably accelerates disease progression, independently of its initial stage 12,57 .…”

Section: Treatment Strategymentioning

confidence: 99%

“…Smoking cessation interventions have proved beneficial even in patients with severe COPD (ref. 56 ).…”

Section: Treatment Strategymentioning

confidence: 99%

Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care

Koblížek

Chlumský²,

Zindr³

et al. 2013

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

126

116

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“…If a smoking habit stops before 30 years of age, the mortality from lung cancer decreases to values similar to those for the population that never smoked. [11][12][13][14] A tobacco addicted patient requires comprehensive management with cognitive behavioral therapy and, at times, medication management. This strategy allows the patient to revert his or her learning of smoking as a coping mechanism and modifies what the smoker thinks and does.…”

Section: Introductionmentioning

confidence: 99%

Proposals for the prevention of lung cancer in the health system of Mexico

et al. 2016

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The management of lung cancer is challenging. However, nowadays the main goal is to achieve a significant overall survival accompanied by a good quality of life. Because smoking is associated with up to 71% of cancer deaths, the first policy that should be established is one that promotes strategies for healthy lifestyles by providing information about lung cancer, risk factors, protection factors, and precautionary data. Furthermore, an effective screening method that would allow early diagnosis should be established. Following diagnosis, the patient should be genotyped to identify predisposing mutations to give personalized medicine to the patient. The health system policies should include information that affects the health of the population and simultaneously allows for early diagnoses, resulting in a higher survival rate.Keywords: carcinoma; non-small-cell lung; public health, primary prevention; secondary prevention; early diagnosis ResumenEl manejo del cáncer de pulmón es un reto que tiene como objetivo una supervivencia global significativa que se vea rodeada de una buena calidad de vida. Si se considera que el tabaquismo está asociado hasta con 71% de las muertes por cáncer, la primera política que debe establecerse es la de proporcionar información sobre el cáncer de pulmón, factores de riesgo, factores de protección y datos de alarma mediante una estrategia de salud de línea de vida, además del establecimiento de un método de tamizaje efectivo que permita un diagnóstico temprano. Después del diagnóstico, debe realizarse una genotipificación para identificar mutaciones sensibles y para proporcionar un tratamiento personalizado al paciente. Las políticas del sistema de salud deben incluir información para que la población incida en su salud y también se puedan realizar diagnósticos tempranos que permitan una mayor supervivencia.Palabras clave: carcinoma de pulmón de células no pequeñas; salud pública; prevención primaria; diagnóstico precoz http://dx

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The Effects of a Smoking Cessation Intervention on 14.5-Year Mortality

Abstract: Smoking cessation intervention programs can have a substantial effect on subsequent mortality, even when successful in a minority of participants.

Cited by 1,109 publications

References 113 publications

Smoking‐Related Mortality in Patients With Early Rheumatoid Arthritis: A Retrospective Cohort Study Using the Clinical Practice Research Datalink

Smoking‐Related Mortality in Patients With Early Rheumatoid Arthritis: A Retrospective Cohort Study Using the Clinical Practice Research Datalink

Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care

Proposals for the prevention of lung cancer in the health system of Mexico

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