The Effects of Aging, Vascular Disease and Hypertension on the Peripheral Pulse Volume

Allison, Robert D.

doi:10.1111/j.1532-5415.1968.tb03968.x

Cited by 11 publications

(2 citation statements)

References 8 publications

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“…In contrast, the degree of asymmetry in the distribution of pulse amplitude defines the magnitude of any abnormality in patients with vascular disease. This method of summarizing data and presenting information in a qualitative profile manner for rapid comparisons does not detract from the importance of the quantitative blood pulse volume and blood flow data necessary for defining the severity of abnormally perfused areas (11). Electrical impedance data are extremely useful in the quantitative evaluation of perfusion to the extremities following identification of a probable vascular lesion through the vascular profile test and silhouette characteristics.…”

Section: Discussionmentioning

confidence: 99%

Vascular Profile Screening Tests: A New Approach to the Detection of Vascular Disease

Allison

1969

J American Geriatrics Society

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By means of a four‐electrode plethysmograph, blood pulse volume changes were determined over the head, neck torso and extremities in healthy subjects and in patients with vascular disease in these areas. The amplitudes of the recorded pulses, plotted bilaterally from the central line of a body silhouette, provided an outline or profile of the vascular supply. In healthy subjects the characteristic outline was symmetrical, but in patients with vascular disease it was asymmetrical in the specific areas involved. Such qualitative identification of vascular abnormalities according to recognized patterns decreases the time required to evaluate numerical data, and indicates the vascular areas in which there should be more quantitative assessment. This screening procedure is useful for the detection of early vascular disease and, when combined with quantitative evaluation, for a guide in the therapeutic management of older patients with established vascular disease.

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Section: Discussionmentioning

confidence: 99%

Vascular Profile Screening Tests: A New Approach to the Detection of Vascular Disease

Allison

1969

J American Geriatrics Society

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“…Aging of the vascular system is seldom evident before the fourth decade, but can become a disease entity late in life (23). With advancing age, the epithelial cells of the heart increase in volume, but the senile heart is not necessarily a diseased organ (24).…”

Section: Age‐dependent Physiologic and Pathologic Changesmentioning

confidence: 99%

The Geriatric Patient: Age‐dependent Physiologic and Pathologic Changes

Lamy

Kitler

1971

J American Geriatrics Society

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Age-dependent physiologic and pathologic changes are discussed under the categories of the soft tissues, the eardlovascular, digestive, respiratory, skeletal and nervous systems, the genito-urinary tract, the senses, speech, hearing, visual function, and the nutritional state.Aging does not affect the whole organism uniformly; rather, it involves the various organs and organ systems to different degrees and in different fashions. Many ideas have been advanced in an effort to explain the process of aging. It has been viewed simply as a decline in free energy with time, i.e., the energy which is needed by the cell to perform its variojjs functions ( 1). As a consequence of aging, there is a decline in the efficiency of physiologic regulation (2); thus the organism is less resistant to stress than is a younger one. The activities of several enzymes decrease with age, due either to a decrease in the rate of synthesis or a change in enzyme structure (3, 4). Other changes with age are: major structural damage to chromosomes (5), accumulation of organic matter in the soft tissues (6), and an accelerated rate of accumulation of gamma globulin with an accelerated rate of decrease of other serum globulin fractions (7).Aging has also been described as a normal part of the life cycle, an intrinsic process which is genetically determined (8). This may well be based on inborn metabolic defects which could be the basic reason for the physiologic changes observed with aging (9). It has been proposed that certain regions of the DNA molecule may not be accessible for transcription, which in turn could cause decreased protein synthesis. However, an increased rate of protein synthesis has also been proposed, based on the theory that this might be necessary to compensate for inactive enzymes (10). Friedman (11) finds no real, direct evidence that structural protein deteriorates with age but points out that connective tissue increases with age.The process of aging has also been summarized as a gradual loss of functional cells and a gradual impairment of the biochemical processes in those cells which do remain functional (12). Birren (13) attributes the aging

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The use of the electrical-impedance technique for the monitoring of cardiac output and limb bloodflow during anaesthesia

Hill

Lowe

1973

Med. & biol. Engng.

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The Effects of Aging, Vascular Disease and Hypertension on the Peripheral Pulse Volume

Cited by 11 publications

References 8 publications

Vascular Profile Screening Tests: A New Approach to the Detection of Vascular Disease

Vascular Profile Screening Tests: A New Approach to the Detection of Vascular Disease

The Geriatric Patient: Age‐dependent Physiologic and Pathologic Changes

The use of the electrical-impedance technique for the monitoring of cardiac output and limb bloodflow during anaesthesia

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