The Effects of an Amine Fluoride/Stannous Fluoride and an Antimicrobial Host Protein Mouthrinse on Supragingival Plaque Regrowth

Pizzo, Giuseppe; Guiglia, Rosario; Cara, M; Giuliana, G; D’Angelo, Matteo

doi:10.1902/jop.2004.75.6.852

Cited by 7 publications

(3 citation statements)

References 27 publications

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“…In contrast, the plaque reduction was minimal for incisors, especially lower incisor and lingual surface. Similar finding was reported by Pizzo et al [ 35 , 36 ]. It may be argued that the lingual surfaces of lower incisors may not be adequate in evaluating the plaque reduction by the use of mouthrinse, since they are in close contact with the tip of tongue, which may influence the early plaque regrowth.…”

Section: Discussionsupporting

confidence: 92%

Effect of a mouthrinse containing rice peptide CL(14-25) on early dental plaque regrowth: a randomized crossover pilot study

et al. 2015

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BackgroundWe aimed to evaluate clinically the effect of mouthrinse containing a rice peptide on early dental plaque regrowth.MethodsThe study was designed as a double-masked, two-group crossover randomized pilot trial, involving 10 periodontally healthy volunteers. After receiving a professional tooth cleaning at baseline, over the next 3 days each participant refrained from all oral hygiene measures and had two daily rinses with 20 ml of the test mouthrinse containing 0.4 % rice peptide CL(14-25) or placebo rinse. At the end of each experimental period, plaque score was assessed using the modified Volpe’s method, and the participants filled out a questionnaire. Each participant underwent a 7-day washout period followed by a second allocation. The plaque score was the primary outcome of the study and participant perception was the secondary outcome.ResultsNo adverse effects were observed in the participants during the study. Clinically, the mean plaque score of the examined teeth was significantly lower in the test group (2.44 ± 0.74, CI: 1.91–2.96) than the placebo group (2.65 ± 0.63, CI: 2.20–3.10) (P < 0.05). When analyzed according to the type of teeth, a significantly lower score of the premolars/molars was observed in the test group (2.39 ± 0.68, CI: 2.08–2.71) than that in the placebo group (2.66 ± 0.58, CI: 2.39–2.93) (P < 0.05).ConclusionsThe mouthrinse containing 0.4 % rice peptide CL(14-25) was effective in reducing the early regrowth of dental plaque. However, clinical relevance of this efficacy needs to be validated in a future large-scale study.Trial registration: UMIN Clinical Trials Registry (UMIN-CTR) R000014000. Date of formal registration: November 1, 2013.

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Section: Discussionsupporting

confidence: 92%

Effect of a mouthrinse containing rice peptide CL(14-25) on early dental plaque regrowth: a randomized crossover pilot study

et al. 2015

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“…Rinsing with 0.12% CHX alone during prolonged periods, but without professional regular debridement does not appear to reduce subgingival bacterial counts in subjects with periodontitis (Persson et al 2007). In comparison with CHX rinses, no other mouth rinses have shown superiority to control bacterial colonization or gingival inflammation (Moran et al 1992, Jenkins et al 1994, Renton‐Harper et al 1998, Pizzo et al 2004).…”

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confidence: 99%

A randomized, controlled clinical trial on the clinical, microbiological, and staining effects of a novel 0.05% chlorhexidine/herbal extract and a 0.1% chlorhexidine mouthrinse adjunct to periodontal surgery

Duss

Lang

Cosyn³

et al. 2010

J Clinic Periodontology

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“…However, an in vitro study showed that a lactoferrin-containing toothpaste did not show superior antibacterial effects compared to a toothpaste containing the anionic surfactant sodium lauryl sulfate (SLS) [ 38 ]. In addition, Pizzo et al could not find an inhibition of plaque regrowth by using a mouthwash with lactoferrin, lactoperoxidase, and lysozyme [ 39 ]. In patients with xerostomia, products with lactoferrin have been tested [ 40 , 41 , 42 ].…”

Section: Overview On Adjunct Ingredients Used In Hydroxyapatite-based...mentioning

confidence: 99%

Overview on Adjunct Ingredients Used in Hydroxyapatite-Based Oral Care Products

2022

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Hydroxyapatite, Ca5(PO4)3(OH), is a biomimetic active ingredient, which is used in commercial oral care products such as toothpastes and mouthwashes worldwide. Clinical studies (in vivo) as well as in situ and in vitro studies have shown the preventive effects of hydroxyapatite in various field of oral care. In some products, hydroxyapatite is combined with other active ingredients, to achieve an additional antibacterial effect or to promote gum health. This review analyzes the efficacy of six selected natural and nature-inspired ingredients that are commonly used together with hydroxyapatite. These additional actives are either antibacterial (lactoferrin, xylitol, and zinc) or promote gum health (allantoin, bisabolol, and hyaluronic acid). A systematic literature search was performed, and all studies found on each ingredient were analyzed. In summary, all analyzed ingredients mentioned in this review are well described in scientific studies on their beneficial effect for oral health and can be used to expand the preventive effect of hydroxyapatite in oral care products.

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The Effects of an Amine Fluoride/Stannous Fluoride and an Antimicrobial Host Protein Mouthrinse on Supragingival Plaque Regrowth

Cited by 7 publications

References 27 publications

Effect of a mouthrinse containing rice peptide CL(14-25) on early dental plaque regrowth: a randomized crossover pilot study

Effect of a mouthrinse containing rice peptide CL(14-25) on early dental plaque regrowth: a randomized crossover pilot study

A randomized, controlled clinical trial on the clinical, microbiological, and staining effects of a novel 0.05% chlorhexidine/herbal extract and a 0.1% chlorhexidine mouthrinse adjunct to periodontal surgery

Overview on Adjunct Ingredients Used in Hydroxyapatite-Based Oral Care Products

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