This editorial connects each article in this issue to the theme, Challenging Long-Held Assumptions, by raising questions. How do we really determine value in health care? How do good, new ideas make it into practice? Why the untapped potential of Doctor of Nursing Practice preparation? Can we actually teach nursing students creativity? Do virtual group appointments actually work? How in the world do families care for loved ones at home on mechanical ventilation? Can nursing educators truly decolonize their own thinking? Is simulation a poor substitute for clinical placements, or just as good and sometimes better? Can the power of social media be used for good? Can simulation actually make new nurses more likely to call a code when it's needed? How can farm animals help people dealing with mental illness? And a question crucial to us all as human beings: Can forgiveness ever be bad?