The effects of berberine and curcumin on cardiac, lipid profile and fibrosis markers in cyclophosphamide‐induced cardiac damage: The role of the TRPM2 channel
Zübeyir Huyut,
Kenan Yildizhan,
Fikret Altındağ
Abstract:Cyclophosphamide (CYP) is widely used to treat various types of cancer. In addition to the therapeutic properties of this drug, unfortunately, its side effects are still not fully understood. This study investigated the protective effect of curcumin (CURC) and berberine (BER) on CYP‐induced cardiac damage. Thirty‐six male rats were equally divided into the control, dimethyl sulfoxide (DMSO), CYP, CYP + CURC, CYP + BER and CYP + BER + CURC groups. Troponin‐I, Creatine kinase‐myocardial band (CK‐MB), total chole… Show more
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