The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials

Tabrizi, Reza; Saneei, Parvane; Lankarani, Kamran Bagheri; Akbari, Maryam; Kolahdooz, Fariba; Esmaillzadeh, Ahmad; Nadi-Ravandi, Somayyeh; Mazoochi, Majid; Asemi, Zatollah

doi:10.1080/10408398.2018.1507996

Cited by 78 publications

(44 citation statements)

References 37 publications

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“…We believe our study is one of the few to report that coffee consumption was inversely associated with weight gain. Caffeine intake could increase energy expenditure by increasing the body's thermogenesis [57]. In animal models, caffeine suppressed increasing adiposity despite total energy intake [58].…”

Section: Dietary Intake and Habitsmentioning

confidence: 99%

Lifestyle changes associated with COVID-19 quarantine among young Saudi women: A prospective study

et al. 2021

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Background Negative lifestyle behaviors are associated with an increased risk of adverse outcomes from coronavirus disease (COVID-19). This study aimed to assess lifestyle changes affecting weight, sleep, mental health, physical activity, and dietary habits prospectively from before COVID-19 to during lockdown. Methods A total of 297 Saudi women, aged 19–30 years (mean age, 20.7 ± 1.4 years), were interviewed at two time points, before and during the quarantine. The data collected included anthropometrics, sociodemographic data, clinical history, food frequency questionnaire responses, Pittsburgh Sleep Quality Index scores, Global Physical Activity Questionnaire (GPAQ) responses, and Perceived Stress Scale measures. In addition, during quarantine, COVID-19 and nutrition-related information and Generalized Anxiety Disorder-7 and Patient Health Questionnaire-9 scores were collected. Multivariate multinomial logistic regression analysis was used to examine the indicators of weight gain and loss from before COVID-19 (baseline) until during lockdown. Results Although approximately half of the participants did not report a weight change, 30% revealed weight loss and 18%, weight gain. The variables associated with increased weight gain were self-quarantine since COVID-19 started (OR: 5.17, 95% CI: 1.57–17.01, p = 0.007), age (OR: 1.53, 1.03–2.28, p = 0.04), and stress at baseline and during lockdown (OR: 1.15, 1.03–1.29, p = 0.01; OR: 1.10, 1.01–1.19, p = 0.03, respectively). The variables associated with a reduced risk of weight gain were the GPAQ score during lockdown (OR: 0.16, 0.04–0.66, p = 0.01), coffee consumption (OR: 0.36, 0.19–0.67, p = 0.01), and total sleep time (OR: 0.70, 0.51–0.97, p = 0.03). Conclusion While most young Saudi women experienced no weight change during the COVID-19 lockdown, one-third lost weight and a significant proportion gained weight. Factors associated with weight, such as stress, sleep hours, physical activity, and coffee consumption, highlight the need to carefully consider those at risk during future circumstances that may require lockdowns. These factors could also aid in implementing policies for future lockdowns and support those most at risk of gaining weight.

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Section: Dietary Intake and Habitsmentioning

confidence: 99%

Lifestyle changes associated with COVID-19 quarantine among young Saudi women: A prospective study

et al. 2021

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“…The most common, inexpensive, accessible substance which has a property of SSAO inhibition is caffeine-an alkaloid present in coffee beans and green tea leaves and consumed daily worldwide. There are a number of researches stating that it is helpful for weight loss and maintenance [9,10]. However, these researches focus on the ability of caffeine to boost metabolism and increase energy expenditure [11,12].…”

Section: Introductionmentioning

confidence: 99%

Attenuation of Weight Gain and Prevention of Associated Pathologies by Inhibiting SSAO

2020

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Obesity is a worldwide prevalent metabolic disorder that is associated with diabetes, among many other diseases. Bearing this in mind, prevention and treatment ways need to be improved. Notably, activity of the enzyme semicarbazide-sensitive amine oxidase (SSAO) is found to be elevated in overweight subjects. Moreover, SSAO inhibition has resulted in an increase of histamine activity in adipose tissue and the limitation of body fat. The current review aims to overview the risks of obesity, rationalize the molecular ways of SSAO activity, and outline the strategies of inhibiting upregulated enzyme levels. It describes the differences between SSAO inhibitors and advances the prospective agents. Based on evidence, caffeine is proposed as an effective, safe, and reliable choice to inhibit SSAO activity. Furthermore, the histamine in adipocytes has been associated with SSAO activity. Therefore, it is suggested as one of the key compounds to be studied for obesity management. To conclude, inhibiting SSAO may attenuate weight gain and prevent related diseases.

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“…Caffeine, as methyl-xanthine derivatives and adrenergic stimulants, is frequently added to food and herbal supplements due to their stimulating and thermogenic effects [21]. A meta-analysis investigation indicated that caffeine intake (congaing in a weight loss supplement) might promote bodyweight reduction [22]. However, there are reports of the adverse outcomes associated with caffeine uses in non-prescription herbal and nutritional supplements.…”

Section: Discussionmentioning

confidence: 99%

Determining Undeclared Synthetic Pharmaceuticals as Adulterants in Weight Loss Herbal Medicines

Salahshour

Sadeghi

Nazari

et al. 2020

Int J Med Toxicol Forensic Med

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Background: The popularity and use of herbal medicines and supplements are growing worldwide. Herbal anti-obesity products have been considered as suitable alternatives to synthetic pharmaceuticals as they are introduced as harmless natural products. However, some manufacturers often add undeclared synthetic pharmaceuticals to the anti-obesity herbal medicine products to improve their efficacy and potency. The present study aimed to analyze herbal weight loss products collected from the drug market in Bojnurd City, Iran.Methods: Ninety-six herbal drug samples, as weight loss products, were obtained from herb shops and pharmacies in Bojnurd City, Iran. All samples were analyzed to detect undeclared active pharmaceutical ingredients using High-Performance Liquid Chromatography with Diode Array Detector (HPLC-DAD) and Gas Chromatography-Mass Spectrometry (GC-MS) techniques.Results: Caffeine, trimethoxyamphetamine, and vitamin E were identified in herbal weight loss products. Caffeine was detected in 21.8% of the obtained samples, as the most common undeclared active pharmaceutical adulterant. Conclusion: Undeclared active pharmaceutical ingredients in herbal weight loss products could threaten patients’ health. Thus, it is necessary to create awareness through health authorities in this regard.

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The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials

Cited by 78 publications

References 37 publications

Lifestyle changes associated with COVID-19 quarantine among young Saudi women: A prospective study

Lifestyle changes associated with COVID-19 quarantine among young Saudi women: A prospective study

Attenuation of Weight Gain and Prevention of Associated Pathologies by Inhibiting SSAO

Determining Undeclared Synthetic Pharmaceuticals as Adulterants in Weight Loss Herbal Medicines

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