The effects of cashew nut intake on lipid profile and blood pressure: A systematic review and meta-analysis of randomized controlled trials

Jalali, Mohammad; Karamizadeh, Maliheh; Ferns, Gordon A.; Zare, Morteza; Moosavian, Seyedeh Parisa; Akbarzadeh, Marzieh

doi:10.1016/j.ctim.2020.102387

Cited by 33 publications

(30 citation statements)

References 31 publications

(49 reference statements)

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“…The greatest DBP reduction in our meta-analysis was about 0.80 mmHg at a dose of 80 g/d. Other pairwise meta-analyses of RCTs have also indicated that dietary interventions to increase the consumption of pistachios (8), cheshaw (9), and almond (10) can improve levels of blood pressure.…”

Section: Discussionmentioning

confidence: 99%

Dose-dependent effect of nuts on blood pressure: a systematic review and meta-analysis of randomized controlled trials

Jayedi

Mirrafiei

et al. 2021

Preprint

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Objective: Traditional pairwise meta-analyses indicated that nuts consumption can improve blood pressure. We iamed to determine the dose-dependent effect of nuts on systolic (SBP) and diastolic blood pressure (DBP) in adults. Methods: A systematic search was undertaken in PubMed, Scopus, and ISI Web of Science till March 2021. Randomized controlled trials (RCT) evaluating the effects of nuts on SBP and DBP in adults were included. We estimated change in blood pressure for each 20 g/d increment in nut consumption in each trial and then, calculated mean difference (MD) and 95%CI using a random-effects model. We estimated dose-dependent effect using a dose-response meta-analysis of differences in means. The certainty of evidence was rated using the GRADE instrument, with the minimal clinically important difference being considered 2 mmHg. Results: A total of 31 RCTs with 2784 participants were included. Each 20 g/d increase in nut consumption reduced SBP (MD: -0.50 mmHg, 95%CI: -0.79, -0.21; I2 = 12%, n = 31; GRADE = moderate certainty) and DBP (MD: -0.23 mmHg, 95%CI: -0.38, -0.08; I2 = 0%, n = 31; GRADE = moderate certainty). The effect of nuts on SBP was more evident in patients with type 2 diabetes (MD: -1.31, 95%CI: -2.55, -0.05; I2 = 31%, n = 6). The results were robust in the subgroup of trials with low risk of bias. Levels of SBP decreased proportionally with the increase in nuts consumption up to 40 g/d (MD40g/d: -1.60, 95%CI: -2.63, -0.58), and then appeared to plateau with a slight upward curve. A linear dose-dependent reduction was seen for DBP, with the greatest reduction at 80 g/d (MD80g/d: -0.80, 95%CI: -1.55, -0.04). Conclusions: The available evidence provides a good indication that nut consumption can result in a small improvement in blood pressure in adults. Well-designed trials are needed to confirm the findings in long term follow-up.

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Section: Discussionmentioning

confidence: 99%

Dose-dependent effect of nuts on blood pressure: a systematic review and meta-analysis of randomized controlled trials

Jayedi

Mirrafiei

et al. 2021

Preprint

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“…Linoleic acid has beneficial properties for the skin, and, for this purpose, it is widely used in the cosmetics and pharmaceutical industry. Stearic acid has neutral effects on the concentration of LDL cholesterol in blood serum and no cholesterol-lowering impact on human health [45]. Based on UFA/SFA ratio, it is essential to mention that there is a higher amount of unsaturated fatty acids (UFA) in the skin and seed parts of the studied O. dillenii fruits than the juice part, which was found to be richer in saturated fatty acids (SFA).…”

Section: Chemical Composition Of Hexane and Ethyl Acetatementioning

confidence: 99%

Chemical Composition and Physicochemical Analysis of Opuntia dillenii Extracts Grown in Morocco

Loukili

Abrigach

Bnouham

et al. 2021

Journal of Chemistry

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The chemical composition and physicochemical properties of hexane and ethyl acetate extracts of skin, juice, and seeds of Opuntia dillenii fruit collected from three Moroccan regions (Oujda, Nador, and Essaouira) were studied. The study revealed that the seed oil extracts presented the highest yield of 13.12%, followed by the skin fraction (1.77%) and the juice extract (0.49%). The evaluation of fatty acid compositions using GC-MS analysis revealed the presence of linoleic acid as a dominating unsaturated fatty acid with a value of 72.39%, followed by palmitic acid, oleic acid, and stearic acid in all localities. Otherwise, the juice extract of Oujda locality was richer in margaric acid (37.41%), followed by Essaouira skin extract (10.7%) and Oujda seed extract (6.18%). However, the campesterol was detected only in trace in the juice extract. The physicochemical properties of O. dillenii seed oils such as acid value, peroxide value, ester value, pH value, saponification value, density, and refractive index were all found to be in good agreement with the quality criteria for pure and fresh oils. In addition, principal component analysis (PCA) and hierarchical cluster analysis (HCA) were implemented to compare the difference in the chemical composition of the different O. dillenii extracts.

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“…The high levels of vitamin C in the juice gives increased resting vitamin C levels in people who supplemented daily (91). Cashew nut consumption may be able to reduce systolic blood pressure (57).…”

Section: Nutrition and Phytonutrients And Their Potential As Functionmentioning

confidence: 99%

The Nutritional Potential of the Native Australian Green Plum (Buchanania obovata) Compared to Other Anacardiaceae Fruit and Nuts

et al. 2020

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The native Australian green plum (Buchanania obovata) is a small fruit that grows in the northern parts of the Northern Territory and Western Australia. The fruit belongs to the family Anacardiaceae, which includes the other agriculturally important fruit mangoes, pistachios and cashew nuts. The green plum is a favored species of fruit for the Aboriginal communities and an important bush food in the Northern Territory. To date, only minimal scientific studies have been performed on the green plum as a food. This review is about plant foods in the family Anacardiaceae and the key nutritional compounds that occur in these fruit and nuts. It looks at the more traditional nutrient profiles, some key health metabolites, allergens and anti-nutrients that occur, and the role these foods play in the health of populations. This provides a guide for future studies of the green plum to show what nutritional and anti-nutritional properties and compounds should be analyzed and if there are areas where future studies should focus. This review includes an update on studies and analysis of the green plum and how its nutritional properties give it potential as a food for diet diversification in Australia.

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The effects of cashew nut intake on lipid profile and blood pressure: A systematic review and meta-analysis of randomized controlled trials

Cited by 33 publications

References 31 publications

Dose-dependent effect of nuts on blood pressure: a systematic review and meta-analysis of randomized controlled trials

Dose-dependent effect of nuts on blood pressure: a systematic review and meta-analysis of randomized controlled trials

Chemical Composition and Physicochemical Analysis of Opuntia dillenii Extracts Grown in Morocco

The Nutritional Potential of the Native Australian Green Plum (Buchanania obovata) Compared to Other Anacardiaceae Fruit and Nuts

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