The effects of chromium supplementation on serum glucose and lipids in patients with and without non-insulin-dependent diabetes

Abraham, Abraham S.; Brooks, Baruch; Eylath, Uri

doi:10.1016/0026-0495(92)90318-5

Cited by 152 publications

(96 citation statements)

References 19 publications

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“…Similarly, in gestational diabetes, 8 g ⅐ kg Ϫ1 ⅐ day Ϫ1 of chromium was more effective than 4 g ⅐ kg Ϫ1 ⅐ day Ϫ1 (396). In contrast, two welldesigned studies in the U.S. (398,399) and two in Finland (400,401) failed to demonstrate any significant benefit of chromium supplementation in patients with diabetes. The latter studies used chromium chloride, which may not be as bioavailable as chromium picolinate.…”

Section: Antioxidants and Vitaminsmentioning

confidence: 98%

Evidence-Based Nutrition Principles and Recommendations for the Treatment and Prevention of Diabetes and Related Complications

et al. 2002

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Section: Antioxidants and Vitaminsmentioning

confidence: 98%

Evidence-Based Nutrition Principles and Recommendations for the Treatment and Prevention of Diabetes and Related Complications

et al. 2002

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“…Zaobserwowano szereg pozytywnych efektów, m.in. obniżenie poziomu cholesterolu ogólnego u ssaków (9, 87, 104) i ptaków (62), jak również obniżenie frakcji LDL u ludzi (104) po podaniu pikolinianu (87) oraz wzrostu frakcji HDL cholesterolu (1, 87) wraz z redukcją trójglicerydów (1). Wpływ suplementacji diety związkami Cr (III) na stężenie cholesterolu HDL nie jest jednak jednoznaczny.…”

Section: Chrom W Badaniach Na Zwierzętach I Ludziachunclassified

Trivalent chromium (CrIII) as a trace element essential for animals and humans

Kosla¹,

Lasocka²,

Skibniewska³

et al. 2018

Medycyna Weterynaryjna

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Trivalent chromium is considered an essential element in the nutrition of both animals and humans. Animal studies confirm many beneficial effects of organic and inorganic chromium compounds on carbohydrate, protein and lipid metabolism in the body. Glucose tolerance factor (GTF) has been demonstrated to involve an active form of trivalent chromium, which sustains normal glucose metabolism. Cr(III) compounds form enzymes and ribonucleic acids, accelerate blood clotting and increase β-glucuronidase activity. Chromium also participates in antioxidant processes, in the synthesis of RNA and DNA and in the immune response, as well as affects secretion of hormones and some vitamins. It has been demonstrated that chromium improves lean body mass in animals, increases growth rate and feed conversion and improves feed intake and energy efficiency. Organic chromium reduces mortality and improves animal reproduction parameters. It also enhances immunity and strengthens response to preventive vaccination. It has been noted in many animal species that a diet low in chromium leads to deficiency symptoms, such as reduced feed intake, lower weight gains, reproductive disorders and increased lipid levels. Chromium deficiency can also result from stress. Moderate chromium deficiency is a risk factor of ischemic heart disease with myocardial infarction. Such a condition may pose a great risk of coronary artery disease. Dietary chromium requirement of an animal body is probably 300 μg Cr/kg d.w. of feed, which is usually satisfied by the ration provided. The highest concentration of chromium is found in the hair, skin and teeth, followed by the liver, kidneys, spleen, and slightly lower in the heart, muscles, pancreas, lungs, bones and brain. Chromium absorption rates in the human intestine range between 0.5 and 2% of the daily intake of inorganic Cr forms, and from 25 to 30% of the element ingested as organic complexes. Clinical studies show that the kinetics of chromium excretion from the system are complex and can be described by a multi-range model, the half-life ranging from 13 min to 192 days. Dietary chromium nanocomposite supplementation (CrNano) used in pigs nutrition has significantly increased Cr content in the blood, longissimus muscle, heart, liver, kidneys, jejunum and ileum. Chromium nanocomposite supplementation acts more effectively on the tissues and, as a consequence, increases the accumulation of the element. .

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“…Chromium supplementation of 200-250 µg/day has resulted in some improvement in glucose tolerance, insulin response and blood lipids in older populations (231,232). However, chromium balance in older adults can be achieved with dietary chromium intakes of < 50 µg/day (233).…”

Section: Chromiummentioning

confidence: 99%

The prevalence and risk factors for age-related macular degeneration in rural–urban India, Sankara Nethralaya Rural–Urban Age-related Macular degeneration study, Report No. 1

Raman

Pal

Ganesan

et al. 2016

Eye

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The effects of chromium supplementation on serum glucose and lipids in patients with and without non-insulin-dependent diabetes

Cited by 152 publications

References 19 publications

Evidence-Based Nutrition Principles and Recommendations for the Treatment and Prevention of Diabetes and Related Complications

Evidence-Based Nutrition Principles and Recommendations for the Treatment and Prevention of Diabetes and Related Complications

Trivalent chromium (CrIII) as a trace element essential for animals and humans

The prevalence and risk factors for age-related macular degeneration in rural–urban India, Sankara Nethralaya Rural–Urban Age-related Macular degeneration study, Report No. 1

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