The Effects of D-Tubocurarine, Hexamethonium and Decamethonium on the Receptor for the Axon Reflex Sweating

Sweating Axon Reflex Produced by Faradic Stimulation and the Site of Its Initiation

“…By the use of the band method, the receptors responsible for the axon reflex sweat responses to nicotine, acetylcholine and sodium chloride have been discriminated from the pathways carrying the axon reflex impulses and the effector endings of the axons in their high susceptibility to certain blocking agents (Wada, Arai, Takagaki and Nakagawa (8) ; Wada (9) ; Wada, Nakagawa, Hanawoka, Hatanaka, Funato, Kanazawa and Morikawa (10)). Ineffectiveness of tetraethylammonium, hexamethonium and decamethonium in blocking the axon reflex response to sodium chloride (8,9,10) indicates that there exists no synaptic transmission by acetylcholine as in the autonomic ganglion.…”

“…Ineffectiveness of tetraethylammonium, hexamethonium and decamethonium in blocking the axon reflex response to sodium chloride (8,9,10) indicates that there exists no synaptic transmission by acetylcholine as in the autonomic ganglion.…”