The Effects of Dietary Pattern during Intensified Training on Stool Microbiota of Elite Race Walkers

Murtaza, Nida; Burke, Louise M.; Vlahovich, Nicole; Charlesson, Bronwen; Neill, Hayley O’; Ross, Megan L.; Campbell, Katrina L.; Krause, Lutz; Morrison, Mark

doi:10.3390/nu11020261

Cited by 72 publications

(69 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We observed a positive tendency for physical activity to be associated with Dorea abundance ( Figure 5H). In a previous study examining elite race walkers with vigorous physical activity, the authors reported an association between Dorea abundance and physical activity, where Dorea was negatively associated with oxygen consumption in a physical economy test [39]. In the case of the family Enterococcaceae, we found positive association with body fat (Figure 5E,F).…”

Section: Discussionsupporting

confidence: 58%

Characterization of the Gut Microbiota of Individuals at Different T2D Stages Reveals a Complex Relationship with the Host

et al. 2020

View full text Add to dashboard Cite

In this work, we studied 217 Mexican subjects divided into six groups with different stages of glucose intolerance: 76 Controls (CO), 54 prediabetes (PRE), 14 T2D no medication (T2D−No−M), 14 T2D with Metformin (T2D−M), 22 T2D with polypharmacy (T2D−P), and 37 T2D with polypharmacy and insulin (T2D−P+I). We aimed to determine differences in the gut microbiota diversity for each condition. At the phylum level, we found that Firmicutes and Bacteroidetes outline major changes in the gut microbiota. The gut bacterial richness and diversity of individuals in the T2D−No−M group were lesser than other groups. Interestingly, we found a significant difference in the beta diversity of the gut microbiota among all groups. Higher abundance was found for Comamonadaceae in PRE, and Sutterella spp. in T2D−No−M. In addition, we found associations of specific microbial taxa with clinical parameters. Finally, we report predicted metabolic pathways of gut microbiota linked to T2D−M and PRE conditions. Collectively, these results indicate that each group has specific predicted metabolic characteristics and gut bacteria populations for each phenotype. The results of this study could be used to define strategies to modulate gut microbiota through noninvasive treatments, such as dietary intervention, probiotics or prebiotics, and to improve glucose tolerance of individuals with prediabetes or T2D.

show abstract

Section: Discussionsupporting

confidence: 58%

Characterization of the Gut Microbiota of Individuals at Different T2D Stages Reveals a Complex Relationship with the Host

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Frequent treatment with antibiotics and/or a regular intake of non-antibiotic drugs have negative effects on the gut microbiota 33–35. Regular exercise and consuming a sport-specific diet are known to be associated with a favourable gut microbiota 36–38. Furthermore, the superdonor should not be a first-degree relative of any of the patients in a trial since the intestinal microbiota is affected by the genetic composition, and a superdonor and recipient with greater genetic similarity may also have greater similarities in their faecal microbiota 39 40.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study

El‐Salhy

Hatlebakk

Gilja

et al. 2019

Gut

363

563

View full text Add to dashboard Cite

ObjectiveFaecal microbiota transplantation (FMT) from healthy donors to patients with irritable bowel syndrome (IBS) has been attempted in two previous double-blind, placebo-controlled studies. While one of those studies found improvement of the IBS symptoms, the other found no effect. The present study was conducted to clarify these contradictory findings.DesignThis randomised, double-blind, placebo-controlled study randomised 165 patients with IBS to placebo (own faeces), 30 g FMT or 60 g FMT at a ratio of 1:1:1. The material for FMT was obtained from one healthy, well-characterised donor, frozen and administered via gastroscope. The primary outcome was a reduction in the IBS symptoms at 3 months after FMT (response). A response was defined as a decrease of 50 or more points in the total IBS symptom score. The secondary outcome was a reduction in the dysbiosis index (DI) and a change in the intestinal bacterial profile, analysed by 16S rRNA gene sequencing, at 1 month following FMT.ResultsResponses occurred in 23.6%, 76.9% (p<0.0001) and 89.1% (p<00.0001) of the patients who received placebo, 30 g FMT and 60 g FMT, respectively. These were accompanied by significant improvements in fatigue and the quality of life in patients who received FMT. The intestinal bacterial profiles changed also significantly in the groups received FMT. The FMT adverse events were mild self-limiting gastrointestinal symptoms.ConclusionsFMT is an effective treatment for patients with IBS. Utilising a well-defined donor with a normal DI and favourable specific microbial signature is essential for successful FMT. The response to FMT increases with the dose.Trial registrationwww.clinicaltrials.gov (NCT03822299) and www.cristin.no (ID657402).

show abstract

“…A KD was seen to exhibit desirable effects on body weight and fat mass in athletes [ 11 , 12 ], however, the effect on lean body mass is yet to be confirmed. No adverse health outcomes were observed on the acid-base status [ 13 ] or mucosal immunity [ 14 ] of athletes but increases in potentially problematic stool microbiota species [ 15 ] were identified. Adherence to a KD tended to have detrimental effects on endurance performance [ 11 , 16 ] but further research is required to determine the true effect of a KD on actual sporting performance.…”

Section: Resultsmentioning

confidence: 99%

Role of a Ketogenic Diet on Body Composition, Physical Health, Psychosocial Well-Being and Sports Performance in Athletes: A Scoping Review

Bowler

Polman

2020

Sports

View full text Add to dashboard Cite

Background: Recently, a focus has been placed on investigating the potential benefits of adherence to a ketogenic diet in enhancing body composition, physical health, psychological well-being, and performance of athletes from various sporting disciplines. As the available research is yet to be collated and analyzed in a single review, this scoping review aims to analyze and draw conclusions from the available literature that exists on the efficacy of a ketogenic diet among athletic populations. Methods: Several primary research databases and any relevant citation lists were searched to locate appropriate studies for inclusion in this scoping review. Studies that investigated the effects of adherence to a ketogenic diet (KD), defined by a carbohydrate intake of less than 5% of total energy intake, on body composition, physical health, psychological well-being, and performance among an athletic population were included in the review. From 814 articles screened, 12 were identified as meeting the inclusion criteria and were included in the final scoping review. Results: Adherence to a KD has beneficial effects on body weight and fat mass. Varying effects were identified on physical health with the diet, eliciting positive effects on fat oxidation but potentially deleterious effects on stool microbiota and iron metabolism. Conflicting results were reported regarding the effects of a KD on sporting performance. Benefits were reported regarding athlete well-being following commencement of a KD, but only after week two. Conclusions: The results of this scoping review demonstrate that there are both beneficial and detrimental effects associated with adherence to a KD among athletic populations. It is understood that further research is required to make any concrete recommendations regarding a KD to athletes.

show abstract

The Effects of Dietary Pattern during Intensified Training on Stool Microbiota of Elite Race Walkers

Cited by 72 publications

References 32 publications

Characterization of the Gut Microbiota of Individuals at Different T2D Stages Reveals a Complex Relationship with the Host

Characterization of the Gut Microbiota of Individuals at Different T2D Stages Reveals a Complex Relationship with the Host

Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study

Role of a Ketogenic Diet on Body Composition, Physical Health, Psychosocial Well-Being and Sports Performance in Athletes: A Scoping Review

Contact Info

Product

Resources

About