The Effects of Dosage and Administration of Two Mercurials on Mercury Retention in Two Strains of Chickens ,

Miller, V. L.; Larkin, Donna V.; Bearse, Gordon E.; Hamilton, C. M.

doi:10.3382/ps.0460142

Cited by 23 publications

(6 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These bivalve and sediment concentrations are all below the dietary threshold for adverse effects in poultry [52,53] as well as fish and wildlife [54]. However, the liver selenium concentrations in the surf scoters from these water bodies are in the range considered for the diagnosis of poultry selenium toxicosis, and the liver manganese values of these birds lie within the ranges deemed high or toxic for poultry [41]. The data display higher accumulation of selenium, manganese, cadmium, and mercury by the scoters compared to the coots.…”

Section: Bioaccumulationmentioning

confidence: 99%

“…Examination of the coefficients implies that the strength of in vivo selenium interaction follows the order Hg Ͼ Mn Ͼ Cd with a molal ratio of 10 to 1.7 to 1. The relative liver accumulation from diet rates in poultry are 230 (Hg as C 6 H 5 HgCH 3 CO 2 and HgCl 2 average) to 1 (Mn as MnO and MnO 2 average) to 500 (Cd as CdCO 3 ) [41][42][43][44][45], whereas the average lithosphere concentration ratio of mercury, manganese, and cadmium is 1 to 2,000 to 2 [46]. These results suggest the possibility of a biogeochemical interaction/environmental exposure linkage between Hg, Mn, Cd, and Se accumulation.…”

Section: Cd-mn-se-hg-as Clustermentioning

confidence: 99%

See 1 more Smart Citation

Biogeochemical interactions affecting hepatic trace element levels in aquatic birds

Möller

1996

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Abstract-Knowledge of elemental interactions is important to the toxicological assessment of wildlife in the geochemical environment. This study determines the concentrations of Al, As, B, Ba, Be, Cd, Cr, Cu, Fe, Pb, Li, Mg, Mn, Hg, Mo, Ni, Se, Ag, V, and Zn in aquatic bird liver, fish liver, whole bivalves, insects, and waters in several aquatic ecosystems in northern California. There is evidence of strong in vivo and environmental interactions, including the observation of manganese as a possible cofactor or indicator in selenium bioaccumulation. The nearest neighbor selenium correlation in aquatic bird liver tissue that results from this work is Cd-Mn-Se-HgAs. The correlation of liver selenium to manganese in vivo and the result that the majority of the variance in liver selenium concentration is contained in the manganese term of the regression model relating Se to Cd, Mn, and Hg is new knowledge in the study of aquatic birds. A linear relationship between liver selenium and environmental manganese (water and sediment) is found in the data, suggesting a water chemistry compartmentalization or activation of toxicants. Alternatively, the hepatic concentrations of selenium, manganese, and iron suggest induction of enzymes in response to oxidative stress.

show abstract

Section: Bioaccumulationmentioning

confidence: 99%

Section: Cd-mn-se-hg-as Clustermentioning

confidence: 99%

Biogeochemical interactions affecting hepatic trace element levels in aquatic birds

Möller

1996

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

show abstract

“…Kiwimae et al (3) found methylmercury in tissues of chickens fed inorganic mercury in the diet. The metabolism of mercury is affected by strain differences in birds (13), and probably intestinal microorganisms in different avian species variously affect the methylation reaction.…”

mentioning

confidence: 99%

Eggshell Thinning in Japanese Quail Fed Mercuric Chloride

Stoewsand

Anderson

Gutenmann

et al. 1971

Science

View full text Add to dashboard Cite

show abstract

“…The values on percent conversion of EMC to inorganic mercury in liver, kidney, and blood agree very well with those reported by Miller et al (1961), using the Sprague-Dawley strain rats, and they are higher than those reported by Takeda and Ukita (1970), using male Donryu rats. A difference in metabolism of mercurial compounds also has been reported in different strains of mice (Miller and Csonka 1968) and chicks (Miller et al 1959(Miller et al , 1967.…”

Section: Discussionmentioning

confidence: 99%

Uptake, distribution, and metabolism of inhaled ethylmercuric chloride in the rat

Fang

Fallin

1973

Arch. Environ. Contam. Toxicol.

View full text Add to dashboard Cite

COMMUNICATED BY LOUIS LYKKENThe uptake and the tissue distribution of ethylmercuric chloride (EMC) by inhalation and oral administration were studied in adult female rats. The pulmonary uptake of EMC linearly increases with the time of exposure and is proportional to the concentration of EMC vapor. With the exception of stomach, intestine, and hair, the tissue distribution of 2 o 3 Hg from pulmonary uptake is quite similar to that from oral administration. The biological halflife of EMC in the organs is longer from pulmonary uptake than from oral administration. Kidney and liver convert EMC to inorganic mercury irrespective of the routes of administration. A small amourit of 2°3Hg is found in the fetus, and the fetal liver accumulates more 2°3Hg than the fetal kidney.Alkyl mercurial pesticides were introduced during the 1940s for seed dressing and, also, for control of fungus disease in plants. These mercury preparations usually contain methyl mercury and, to a less extent, ethyl mercury. The short-chained alkyl mercury salts vaporize easily at room temperature and poisoning occurs after exposure to these vapors CSwensson t952, Trachtenberg 1969). Studies on the uptake and distribution of mercury vapor through inhalation have been made in a number of animals (Gage 1961, Hayes and Rothstein 1962, Magos 1967, 1968, Berlin et al., 1969, Cassano et al. 1969. However, detailed reports are not available regarding the respiratory uptake of alkyl mercury compounds. The retention of dimethyl mercury after a single inhalation exposure by mice under slight anesthesia has been reported (Ost]und 1969) but the vapor concentrations used were not given. This paper reports the uptake, distribution, and metabolism of ethylmercuric chloride (EMC) in rats as the result of inhalation of EMC and, for comparison, ingestion of the chemical. Materials and methods2°3Hg-labeled ethylmercuric chloride (EMC3°3Hg) was prepared by an exchange reaction. One mmole of pure, recrystalized ethylmercuric chloride was dissolved in five 1Technical Paper No. 3496, Oregon Agricultural Experiment Station, Corvallis, Oregon.

show abstract

The Effects of Dosage and Administration of Two Mercurials on Mercury Retention in Two Strains of Chickens ,

Cited by 23 publications

References 7 publications

Biogeochemical interactions affecting hepatic trace element levels in aquatic birds

Biogeochemical interactions affecting hepatic trace element levels in aquatic birds

Eggshell Thinning in Japanese Quail Fed Mercuric Chloride

Uptake, distribution, and metabolism of inhaled ethylmercuric chloride in the rat

Contact Info

Product

Resources

About