The effects of ECT on cognitive functioning in the elderly: a review

Tielkes, Caroline E.M.; Comijs, Hannie C.; Verwijk, Esmée; Stek, Max L.

doi:10.1002/gps.1989

Cited by 51 publications

(42 citation statements)

References 39 publications

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“…Unfortunately, studies of the cognitive side effects of ECT in the elderly are sparse, and often suffer from methodological flaws, (Gardner & O'Connor, 2008;Tielkes, Comijs, Verwijk, & Stek, 2008). They usually measure cognitive side effects at one time point within one month after a course of ECT, although it is desirable to investigate both short-term and long-term side effects.…”

Section: Introductionmentioning

confidence: 99%

The Role of Baseline Cognitive Function in the Neurocognitive Effects of Electroconvulsive Therapy in Depressed Elderly Patients

Dybedal

Tanum

Bjølseth

2015

The Clinical Neuropsychologist

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Section: Introductionmentioning

confidence: 99%

The Role of Baseline Cognitive Function in the Neurocognitive Effects of Electroconvulsive Therapy in Depressed Elderly Patients

Dybedal

Tanum

Bjølseth

2015

The Clinical Neuropsychologist

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“…When comparing preand post-ECT functioning, mixed results have been reported on measures of global cognitive functioning and memory, while no changes have been reported on measures of executive function, language, or visuospatial function (for reviews see [59,60]). There are several possible reasons for these divergent findings.…”

Section: Ect and Cognition In The Elderlymentioning

confidence: 96%

Neuromodulation Therapies for Geriatric Depression

Gálvez

Alonzo

et al. 2015

Curr Psychiatry Rep

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Depression is frequent in old age and its prognosis is poorer than in younger populations. The use of pharmacological treatments in geriatric depression is limited by specific pharmacodynamic age-related factors that can diminish tolerability and increase the risk of drug interactions. The possibility of modulating cerebral activity using brain stimulation techniques could result in treating geriatric depression more effectively while reducing systemic side effects and medication interactions. This may subsequently improve treatment adherence and overall prognosis in the older patient. Among clinically available neuromodulatory techniques, electroconvulsive therapy (ECT) remains the gold standard for the treatment of severe depression in the elderly. Studies have proven that ECT is more effective and has a faster onset of action than antidepressants in the treatment of severe, unipolar, geriatric depression and that older age is a predictor of rapid ECT response and remission. The application of novel and more tolerable forms of ECT for geriatric depression is currently being examined. Preliminary results suggest that right unilateral ultrabrief ECT (RUL-UB ECT) is a promising intervention, with similar efficacy to brief-pulse ECT and fewer adverse cognitive effects. Overall findings in repetitive transcranial magnetic stimulation (rTMS) suggest that it is a safe intervention in geriatric depression. Higher rTMS stimulation intensity and more treatments may need to be given in the elderly to achieve optimal results. There is no specific data on vagus nerve stimulation in the elderly. Transcranial direct current stimulation, magnetic seizure therapy and deep brain stimulation are currently experimental, and more data from geriatric samples is needed.

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“…Standardized measurements of how effective and safe the treatment is do not exist. For example, Tielkes, Comijs, Verwijk, and Stek (2008) reviewed 15 studies on the cognitive effects of ECT on the elderly. They found that the studies varied widely in how they measured cognitive functioning.…”

Section: How Reliable Are Ect Studies?mentioning

confidence: 99%

Electroshock: A Discerning Review of the Nursing Literature

Daalen-Smith

Gallagher

2011

Issues in Mental Health Nursing

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Electroshock, better known as Electroconvulsive Therapy (ECT) has sporadically received generous attention in North American Literature. An examination of the nursing literature regarding ECT reveals an expectation for nursing to play an important role in patient education and compliance. Further, while the literature remains somewhat divided on the efficacy of electroshock, there appears to be a pro-ECT bias and an absence of first-person accounts: two areas of importance for nurse researchers and scholars to address.

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The effects of ECT on cognitive functioning in the elderly: a review

Cited by 51 publications

References 39 publications

The Role of Baseline Cognitive Function in the Neurocognitive Effects of Electroconvulsive Therapy in Depressed Elderly Patients

The Role of Baseline Cognitive Function in the Neurocognitive Effects of Electroconvulsive Therapy in Depressed Elderly Patients

Neuromodulation Therapies for Geriatric Depression

Electroshock: A Discerning Review of the Nursing Literature

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