2021
DOI: 10.47611/jsrhs.v10i4.1843
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The Effects of Glycerol on Biofilm Production

Abstract: Due to the widespread, antibiotic-resistant nature of biofilm-producing bacteria, there is high demand for research on biofilm formation.  This research serves as a contribution to the existing knowledge of how biofilms form.  Its results could shed light on how biofilm-producing bacteria utilize communication pathways in response to environmental and chemical stimuli.  To determine the effects of glycerol (a sugar alcohol linked to osmotic stress) on biofilm production, Pseudomonas fluorescens strain SBW25 wa… Show more

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“…This impacted their chemical profile (Figures 1 and 2) by being S8 rich in free amino acids and glycerol while being S2 rich in benzoic acid, trigonelline, formic acid, and choline. If free amino acids are known to have no influence on the biofilm formation and development phase [48], the other compounds are known to interact negatively with biofilm formation [49][50][51]. Despite their different composition, neither showed any inhibitory activity on the growth of planktonic cells, with no observable MIC (Minimum Inhibitory Concentration) values.…”
Section: Discussionmentioning
confidence: 99%
“…This impacted their chemical profile (Figures 1 and 2) by being S8 rich in free amino acids and glycerol while being S2 rich in benzoic acid, trigonelline, formic acid, and choline. If free amino acids are known to have no influence on the biofilm formation and development phase [48], the other compounds are known to interact negatively with biofilm formation [49][50][51]. Despite their different composition, neither showed any inhibitory activity on the growth of planktonic cells, with no observable MIC (Minimum Inhibitory Concentration) values.…”
Section: Discussionmentioning
confidence: 99%