2018
DOI: 10.26641/2307-0404.2018.1(part1).127251
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The effects of gut indigenous microbiota on intensity of oxidative stress and the cytokine immunity in women with recurrent pyelonephritis.

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Cited by 4 publications
(6 citation statements)
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“…Tasian and colleagues (16) have identified a strong association between oral antibiotics and the risk of nephrolithiasis which remains elevated for up to five years from antibiotic exposure. These results also accord with our earlier studies, which reported a strong association between antibiotics administration, intestinal barrier dysfunction and hyperoxaluria formation (15,18,25). In view of all that has been mentioned so far, one may suppose that Lactobacillus and Bifidobacterium deficiency leads to intestinal barrier dysfunction, violation of oxalate transport mechanisms in intestinal epithelium (both secretion and absorption) and a decrease in total ODA in fecal microbiota in PD patients.…”
Section: Discussionsupporting
confidence: 92%
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“…Tasian and colleagues (16) have identified a strong association between oral antibiotics and the risk of nephrolithiasis which remains elevated for up to five years from antibiotic exposure. These results also accord with our earlier studies, which reported a strong association between antibiotics administration, intestinal barrier dysfunction and hyperoxaluria formation (15,18,25). In view of all that has been mentioned so far, one may suppose that Lactobacillus and Bifidobacterium deficiency leads to intestinal barrier dysfunction, violation of oxalate transport mechanisms in intestinal epithelium (both secretion and absorption) and a decrease in total ODA in fecal microbiota in PD patients.…”
Section: Discussionsupporting
confidence: 92%
“…In the context of dysbiosis, the only possible explanation for greater total fecal ODA loss in PD patients compared with HD patients may be the frequent use of antibiotic therapy for PD-associated infections (31). Significant contribution of ODB to oxalate homeostasis (reducing oxalate absorption and subsequent urinary excretion) after antibiotic treatment has been profoundly described (15)(16)(17)(18). Georgieva et al (29) have highlighted that most strains of the Lactobacillus and Bifidobacterium group are susceptible to the main antibiotic classes.…”
Section: Discussionmentioning
confidence: 99%
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“…High levels of TNF-α, MCP-1 and IL-23 in the blood in adults and children confirm their important role in both AP and ChP, but MCP-1 can be considered as an indicator of acute / exacerbation of chronic pyelonephritis [10,11].…”
Section: Original Papersmentioning
confidence: 99%
“…Patients with RUTIs must constantly take antibiotics, including long-term antibiotic prophylaxis ( Fine et al, 2019 ; Issakhanian and Behzadi, 2019 ; Toor et al, 2019 ; Meštrović et al, 2020 ). Although antibiotics prevent UTI recurrences, antibiotic-induced dysbiosis leads to increased production and accumulation of LPSs and other toxic products of bacterial activity (e.g., P-cresol, trimethylamine-N-oxidoreductase, and indoxyl sulfate) and intestinal epithelial barrier dysfunction that accelerates excessive production of cytokines and chemokines and facilitates their translocation, which causes extraintestinal and/or systemic inflammation ( Driyanska et al, 2014 ; Francino, 2016 ; Stepanova et al, 2018a ; Gagliardi et al, 2018 ). It should be noted that the effect of antibiotics on intestinal barrier function is still poorly understood.…”
Section: Introductionmentioning
confidence: 99%