The effects of hippocampal system lesions on a novel temporal discrimination task for rats

Kyd, Rachel J.; Pearce, John M.; Haselgrove, Mark; Amin, Eman; Aggleton, John Patrick

doi:10.1016/j.bbr.2007.09.010

Cited by 30 publications

(45 citation statements)

References 55 publications

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“…It is important to emphasize that a lesion-induced alteration in the content of duration memory is entirely consistent with some prospective timing studies in animals that reported no effect of hippocampal damage [75,76]. Consider a duration comparison paradigm wherein the animal must make one response for a reward ('press left lever') if it The peak interval (PI) procedure is an ideal screen for prospective duration memory.…”

Section: Animal Studies Of Prospective Duration Memorymentioning

confidence: 99%

Prospective and retrospective duration memory in the hippocampus: is time in the foreground or background?

MacDonald

2014

Phil. Trans. R. Soc. B

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Psychologists have long distinguished between prospective and retrospective timing to highlight the difference between our sense of duration during an experience in passing and our sense of duration in hindsight. Humans and other animals use prospective timing in the seconds-to-minutes range in order to learn durations, and can organize their behaviour based upon this knowledge when they know that duration information will be important ahead of time. By contrast, when durations are estimated after the fact, thus precluding the subject from consciously attending to temporal information, duration information must be extracted from other memory representations. The accumulated evidence from prospective timing research has generally led to the hippocampus (HPC) being casted in a supporting role with prefrontalstriatal, cortical or cerebellar circuits playing the lead. Here, I review findings from the animal and human literature that have led to this conclusion and consider that the contribution of the HPC to duration memory is understated because we have little understanding about how we remember duration.

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Section: Animal Studies Of Prospective Duration Memorymentioning

confidence: 99%

Prospective and retrospective duration memory in the hippocampus: is time in the foreground or background?

MacDonald

2014

Phil. Trans. R. Soc. B

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“…1 Such an interpretation is consistent with the more general suggestion that the hippocampus is involved in maintaining stimulus representations across time (e.g., Rawlins 1985;Rodriguez and Levy 2001;Woodruff-Pak and Disterhoft 2008;Ludvig et al 2009). However, it must be acknowledged that this hypothesis has to be incomplete, as it has been reported that subjects with complete hippocampal lesions are still able to form associations between CSs and appetitive USs separated by relatively long gaps (Kyd et al 2007;Lin and Honey 2011). Perhaps the DHPC is responsible for maintaining specifically temporal aspects of the stimulus trace that are not required for successful trace conditioning, but in the absence of further experimental work this must remain speculative.…”

Section: Maintaining Temporal Information In the Absence Of The Csmentioning

confidence: 99%

Dorsal hippocampal involvement in conditioned-response timing and maintenance of temporal information in the absence of the CS

2013

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“…Thus far, using rats, an asymmetry has been found between discriminations based on the intensity of sound (Zieliński & Jakubowska, 1977), the length of an object (Kosaki et al, 2013), and the duration of an auditory cue (Kyd et al, 2008). It remains to be determined with this species whether a similar asymmetry can be found when the discrimination involves differences in quantity.…”

mentioning

confidence: 94%

“…This effect has been found with discriminations based on different intensities of white noise, using conditioned suppression with rats (Zieliński & Jakubowska, 1977); different intensities of odors, using appetitive conditioning with bees (Pelz, Gerber, & Menzel, 1997); different lengths of panels, using escape from a swimming pool with rats (Kosaki, Jones, & Pearce, 2013); different durations of an auditory stimulus, using appetitive conditioning with rats (Kyd, Pearce, Haselgrove, Amin, & Aggleton, 2008;Todd, Winterbauer, & Bouton, 2010); and different numbers of the same objects, for appetitive conditioning with brown bears (Vonk & Beran, 2012) and pigeons (Inman, Honey, & Pearce, 2015;Watanabe, 1998).…”

mentioning

confidence: 99%

Asymmetry in the discrimination of quantity by rats: The role of the intertrial interval

et al. 2015

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In three experiments, rats were trained to discriminate between 20 and five (Exps. 1 and 2), or between 40 and five (Exp. 3), black squares. The squares were randomly distributed in the center of a white background and displayed on a computer screen. For one group, the patterns containing the higher quantity of squares signaled the delivery of sucrose (+), whilst patterns with the lower quantity of squares did not (-). For the second group, sucrose was signaled by the lower, but not by the higher, quantity of squares. In Experiment 1, the intertrial interval (ITI) was a white screen, and the 20+/5-discrimination was acquired more readily than the 5+/20-discrimination. For Experiment 2, the ITI was made up of 80 black squares on a white background. In this instance, the 5+/20-discrimination was acquired more successfully than the 20+/5-discrimination. In Experiment 3, two groups were trained with a 40+/5-discrimination, and two with a 5+/40-discrimination. For one group from each of these pairs, the training trials were separated by a white ITI, and the 40+/5-discrimination was acquired more readily than the 5+/40-discrimination. For the remaining two groups, the training trials were not separated by an ITI, and the two groups acquired the task at approximately the same rate. The results indicate that the cues present during the ITI play a role in the asymmetrical acquisition of magnitude discriminations based on quantity.

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The effects of hippocampal system lesions on a novel temporal discrimination task for rats

Cited by 30 publications

References 55 publications

Prospective and retrospective duration memory in the hippocampus: is time in the foreground or background?

Prospective and retrospective duration memory in the hippocampus: is time in the foreground or background?

Dorsal hippocampal involvement in conditioned-response timing and maintenance of temporal information in the absence of the CS

Asymmetry in the discrimination of quantity by rats: The role of the intertrial interval

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