The effects of intravenously administered bombesin on pentagastrin-stimulated acid secretion in cats

Bado, André; Lewin, M. J. M.; Dubrasquet, M

doi:10.1016/0167-0115(88)90098-5

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Animals and Surgery1

Gastric Secretory Studies1

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1988

2002

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Cited by 5 publications

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“…At this time, the MS carried H. felis and the HFP was bacterium free. The present model has been validated for functional gastric studies as previously described (4,5,19). Briefly, to verify the vagotomized status of the HFP, cats fasted for 18 h were injected with 2-deoxy-D-glucose (100 mg/kg iv) with the fistula of the MS closed.…”

Section: Animals and Surgerymentioning

confidence: 99%

“…We then investigated the effects of the PAF receptor antagonist SR-27417A (1 mg/kg) and of the H 3 receptor antagonist thioperamide (0.3 mg/kg or 10 nmol/kg) on stimulated gastric acid output. These drugs have been shown to modify gastric acid secretion at dosages indicated here (4,5,48). They were injected as an intravenous bolus just before a continuous intravenous infusion of pentagastrin (16 g ⅐ kg Ϫ1 ⅐ h Ϫ1 ) or histamine (100 g ⅐ kg Ϫ1 ⅐ h Ϫ1 ) started.…”

Section: Gastric Secretory Studiesmentioning

confidence: 99%

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