This study seeks to ascertain and document the extent to which investment in IT by banks in Ghana can impact on their profitability using the Balanced Scorecard (BSC) framework. The study uses the extensive panel dataset of 15 banks sampled from the Ghanaian banking industry over a 10-year period (1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007). The study finds that banks which maintain high levels of investments in IT increased return on assets (ROA) and return on equity (ROE). Keywords: Balanced Scorecard, IT, ROA, ROE, Performance, Banks, Ghana 1. Introduction According to Levitt (1992), technology presents itself as a powerful force that drives the world towards a converging commonality. From the beginning of human era, technology has been one of the most essential and most important factors for the development of mankind (Coombs et al., 1987). Innovations in information processing, telecommunications, and related technologies -known collectively as "Information Technology" (IT) or sometimes Information Communication Technologies (ICTs) -is defined by Ige (1995) as the modern handling of information by electronic means, which involves its access, storage, processing, transportation or transfer and delivery. Langdon and Langdon, (2006) also define IT as a set of interrelated components that collect (or remove), process, store and distribute information to support decision making, co-ordination and control. IT also helps managers and workers to analyse problems, visualize complex subjects and create new products. IT including computer based information systems used by an organisation and their underlying technologies have propelled changes in the banking sector (Langdon and Langdon, 2006). Technological innovation for that matter affects not just banking and financial services, but also the direction of an economy and its capacity for continual and sustainable growth. Most banking industry and development analysts assert that technological change is one of the important factors underlying the dynamics in the banking industry structure and performance today which leads to cost competitiveness and diversification into new lines of business to improve profitability, through strategic positioning and processes. In order to either sustain or enhance on their competitive advantage in an ostensibly growing industry, banking institutions invest fortune or substantial amounts in IT resources, which could also reveal new means of creating value for both the bank and the customer. However, expenditures that affect banks' ability to compete are usually discretionary. These expenditures are made to sustain or increase shareholder value through (1) a revenue growth strategy by expanding into new markets, new customers, products and services and (2) a productivity strategy whereby improvements are made in the cost structure and in asset utilization. Technology is being increasingly employed in service organisations to enhance customer service quality and delivery, reduce costs, and standardise core servic...