Abstract-The articles describe the design and results of study of specifications of a drill and milling chuck.The results of the study eccentric chuck rounds with the key in static and during cutting. A feature of the chuck used in manual, pneumatic and electric drills drilling, CNC milling, multi-purpose, woodworking and other machines , the existence of two kinematics chains, it possible to obtain high gain and reinforce the rigidity of the cutting tool with a cylindrical shank. This demonstrates the effectiveness of their use in the Machine-assembling manufacture.Eccentric drilling and milling chuck designed for fast and secure clamping tools with cylindrical shank (drills, countersinks, reamers, milling cutters, etc.) right and left but self-rotation within specified range and other multi-purpose machines. Chuck design is to provides fast replacement tool, accuracy, durability, and reliable clamping of the hand or a key on a principle of self-locking chucks efficiently and conveniently used in surgical operations -for opening holes in the bones, that require low weight and dimensions as well as the reliability of fixation drill or other tool with quick changeover to another clamp diameter.