DOI: 10.26686/wgtn.16973734
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The Effects of Microtubule Stabilizing Drugs on Macrophage Immune-Mediated Endocytosis

Abstract: <p>Microtubule stabilizing drugs (MSD) bind and stabilize microtubules, thus inhibiting their normal function. MSD exhibit anti-mitotic effects which makes them attractive as cancer chemotherapeutics and much of existing research has focused on these effects in proliferating cells. In contrast, we are interested in assessing the effects of microtubule stabilization on non-proliferating cells, such as macrophages, to determine potential mitosis-independent actions of MSD on microtubule function. Thus, we … Show more

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