The effects of mindfulness and health education programs on the emotional state and cognitive function of elderly individuals with mild cognitive impairment: A randomized controlled trial

Klainin‐Yobas, Piyanee; Kowitlawakul, Yanika; Lopez, Violeta; Tang, Chao Tian; Hoek, Kua E.; Gan, Goh Lee; Feng, Lei; Rawtaer, Iris; Mahendran, Rathi

doi:10.1016/j.jocn.2019.05.031

Cited by 50 publications

(52 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For example, in Shomaker research, mindfulness training reduced insulin resistance in diabetic adolescents with one-year follow-up (8).Also various meta-analysis showed that vitamin D can reduce insulin resistance in different physical conditions (23,24). About cognitive function Klainin-Yobas et.al showed that mindfulness can improve cognitive function and emotional state in elderly individuals with moderate cognitive impairment (25). Moreover, in a randomized control trial, Byrn et.al reported that vitamin D supplementation in a variety of dosages can improve cognition in patients with T2DM (26).…”

Section: Resultsmentioning

confidence: 99%

The synergistic effect of vitamin D supplement and mindfulness on insulin resistance and different aspects of cognitive function in vitamin D deficient type 2 diabetic mellitus women: A pilot randomized clinical trial with placebo-controlled

Davoudi

Rezaie

Ahmadi

et al. 2021

Preprint

View full text Add to dashboard Cite

Purpose This study aimed to examine the synergistic effect of Vitamin D (VD) supplement and mindfulness on insulin resistance and different aspects of cognitive function in VD deficient type 2 diabetic women. Methods In this randomized-controlled trial, totally 225 women with type 2 diabetes mellitus (T2DM) and VD deficiency were randomly allocated to five groups: (1) mindfulness, (2) mindfulness and VD, (3) mindfulness and placebo, (4) VD, and (5) placebo. Mindfulness includes 12 sessions and VD patients received a daily 4000 IU oral dosage (two capsules) with 28,000 IU vitamin D weekly for 12 weeks. Sun exposure, anthropometric indices, dietary intake, physical activity, energy levels, and laboratory analyses were measured at the pre-test and after 12-week supplementation. Dependent variables include cognitive function (Risky decision making, IQ and Trail Making Test) and insulin resistance. Results In baseline, measures were not different among the groups. At the end of the treatment, cognitive function results showed improvement for all groups except the “placebo” group. About other groups, there was not any differences between VD and mindfulness groups (or combinations with placebo). However, in “VITAMIN + MINDFULNESS” group, a greater improvement compared to other groups was observed (P < 0.05). This result exactly repeated for insulin resistance. Furthermore, there were not any significant difference among groups for IQ (as one aspect of cognitive function) (P > 0.05). Moreover, there was not any differences among groups for sunlight exposure and BMI (P > 0.05). Only in combined group (VD + Mindfulness) the fasting blood sugar (FBS) significantly reduced that shows the synergistic effect of VD supplementation and Mindfulness (P < 0.05). Conclusion Combining VD Supplementation and mindfulness can reduce insulin resistance and improve different aspects of cognitive function in VD Deficient patients.

show abstract

Section: Resultsmentioning

confidence: 99%

The synergistic effect of vitamin D supplement and mindfulness on insulin resistance and different aspects of cognitive function in vitamin D deficient type 2 diabetic mellitus women: A pilot randomized clinical trial with placebo-controlled

Davoudi

Rezaie

Ahmadi

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…furthermore, vitamin D has a vital role in healthy brain function and de ciency of vitamin D may lead to cognitive impairment (28) and vitamin D supplements improved cognitive function in various medical papulations (29,30). Also, mindfulness by affecting on dlpfc, amygdala, PFC and limbic system, has revealed improvements in cognitive functions (i.e., executive function, working memory and attention ) in younger and older patients (25). So, combination of vitamin D and mindfulness revealed synergistic effects on cognitive functions.…”

Section: Resultsmentioning

confidence: 99%

Synergistic effect of Vitamin D Supplement and mindfulness on insulin resistance and different aspects of cognitive function in Vitamin D Deficient Type 2 Diabetic mellitus (T2DM) women: A pilot randomized clinical trial with placebo-controlled

davoudi

Rezaei

Ahmadi

et al. 2020

Preprint

View full text Add to dashboard Cite

Abstract Purpose This study aimed to examining Synergistic effect of Vitamin D (VD) Supplement and mindfulness on insulin resistance and different aspects of cognitive function in VD Deficient Type 2 Diabetic women. Methods In this randomized-controlled trial, totally 225 women with T2DM and VD deficiency were randomly allocated to five groups: (1) mindfulness, (2) mindfulness and VD, (3) mindfulness and placebo, (4) VD, and (5) placebo. Mindfulness includes 12 sessions and VD patients received a daily 4000 IU oral dosage (two capsules) with 28,000 IU vitamin D weekly for 12 weeks. Sun exposure, anthropometric indices, dietary intake, physical activity, energy levels, laboratory analyses, were measured at the pre-test and after 12-week supplementation. dependent variables include cognitive function (Risky decision making, IQ and Trail Making Test) and insulin resistance. Results In baseline, measures were not different among the groups. At the end of treatment, cognitive function results showed improvement for all groups except the “placebo” group. About other groups, there was not any difference between VD and mindfulness groups (or combinations with placebo). but in “VITAMIN + MINDFULNESS” has a greater improvement rather than other groups (P < 0.05). This result exactly repeated for insulin resistance. However, there were not any significant difference among groups for IQ(P > 0.05). There was any difference among groups for sunlight exposure and BMI (P > 0.05). For FBS only in combined group (VD + Mindfulness) the FBS significantly reduced that is synergistic effects (P < 0.05). Conclusion Combining VD Supplement and mindfulness can reduce insulin resistance and improve different aspects of cognitive function in VD Deficient patients.

show abstract

“…Data from the current study came from two open-label RCTs (Clinical Trial Registry Numbers: NCT02854085 and NCT02286791). The first randomized eligible participants to one of three groups-AT, Music Reminiscence Activity and a no-contact control group (R. Lee et al, 2019), and the second randomized participants to a mindfulness awareness program or an AC group (Klainin-Yobas et al, 2019). Both RCTs had similar assessment and recruitment protocols.…”

Section: Methods Designmentioning

confidence: 99%

“…First, we paired AT with an AC group so as to justify stronger interpretations. It should also be noted that the psychiatric and MMSE scores of this AC group were analyzed previously (Klainin-Yobas et al, 2019), in comparison to a mindfulness meditation group. Second, we analyzed raw cognitive scores, as opposed to normed scores; due to certain artifacts in the norming process, normed scores may not be sensitive in tracking longitudinal changes.…”

Section: Introductionmentioning

confidence: 99%

The Art of Remediating Age-Related Cognitive Decline: Art Therapy Enhances Cognition and Increases Cortical Thickness in Mild Cognitive Impairment

Rawtaer

Goh

et al. 2020

J Int Neuropsychol Soc

Self Cite

View full text Add to dashboard Cite

Objective: Previous research on art therapy (AT) in cognitive aging has been lacking. AT can potentially engender significant cognitive gains, due to its rigorous cognitive involvement, making it useful to tackle age-related cognitive decline. Along with these cognitive gains, associated neuroplastic changes are hypothesized to arise from AT as well. The current intervention examined the effects of an AT intervention on cognitive outcomes and cortical thickness (CT) among participants with mild cognitive impairment. Method: Participants were assigned to AT (n = 22) and an active control group (n = 27). In both, weekly 45-min sessions were carried out across 3 months. Cognitive assessments and structural magnetic resonance imaging scans were carried out at baseline and 3-month follow-up. Whole brain analyses on CT were carried out. Cognitive outcomes were analyzed using hierarchical linear models. Results: Significant gains in immediate memory and working memory span were observed in the AT group, relative to the control group. Significantly increased CT in the AT group, relative to controls, was observed in a right middle frontal gyrus (MFG) cluster. Furthermore, CT changes in this cluster were significantly and positively correlated with changes in immediate memory. Conclusion: These findings highlighted the role of MFG neuroplasticity in enhancing certain cognitive functions in AT. AT is a neuroplastic intervention capable of engendering significant cognitive gains and associated cortical changes in the context of age-related cognitive decline, even when executed as a low-intensity intervention across 3 months. Given the preliminary nature of these findings, future larger sampled studies are needed.

show abstract

The effects of mindfulness and health education programs on the emotional state and cognitive function of elderly individuals with mild cognitive impairment: A randomized controlled trial

Cited by 50 publications

References 40 publications

The synergistic effect of vitamin D supplement and mindfulness on insulin resistance and different aspects of cognitive function in vitamin D deficient type 2 diabetic mellitus women: A pilot randomized clinical trial with placebo-controlled

The synergistic effect of vitamin D supplement and mindfulness on insulin resistance and different aspects of cognitive function in vitamin D deficient type 2 diabetic mellitus women: A pilot randomized clinical trial with placebo-controlled

Synergistic effect of Vitamin D Supplement and mindfulness on insulin resistance and different aspects of cognitive function in Vitamin D Deficient Type 2 Diabetic mellitus (T2DM) women: A pilot randomized clinical trial with placebo-controlled

The Art of Remediating Age-Related Cognitive Decline: Art Therapy Enhances Cognition and Increases Cortical Thickness in Mild Cognitive Impairment

Contact Info

Product

Resources

About