This research aimed to investigate the effects of neurofeedback training on unilateral neglect and depression in patients with stroke. Fourteen of the subjects were selected from the experimental group and the control group respectively; the following results were obtained. First, experimental group and the control group presented significant statistical difference before and after intervention on neglect. However, there is after intervention no significant statistical among them. Two, experimental group and the control group presented significant statistical difference before and after intervention on depression, and the experimental group demonstrated more decrease than the control group in depression. The results obtained from this research expect us that applying the neurofeedback training for the improvement of neglect and depression, to stroke patients has a positive effect on the rehabilitation of patients.