The effects of pelleted cannabidiol supplementation on heart rate and reaction scores in horses

Draeger, Anna L; Thomas, Evan P.; Jones, K.; Davis, Alison; Porr, C. A. Shea

doi:10.1016/j.jveb.2021.09.003

Cited by 14 publications

(23 citation statements)

References 28 publications

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“…2) The anxiolytic effects of CBD are well known ( Ligresti et al., 2016 ; Mason, 2006 ); CBD, by reducing anxiety, reduces the levels of stress, a key factor involved in stereotypies of horses ( Dezfouli et al., 2013 ). Draeger et al. (2021) showed a decrease in the horse's reactivity after supplementation with CBB.…”

Section: Discussionmentioning

confidence: 93%

“…The Authors’ assumption was that lowering the reactivity of the horse could also manipulate how the horse responded to environmental challenges, therefore decreasing stress, and improving animal behaviour and welfare. It is important to point out that the study carried out by Draeger et al. (2021) evaluated the horses after 6 months of supplementation, and that no horse with a stereotypy was assessed.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse

Cunha

Felisardo

Salamanca

et al. 2023

Veterinary and Animal Science

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Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse

Cunha

Felisardo

Salamanca

et al. 2023

Veterinary and Animal Science

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“…Przed i po suplementacji nie zmieniło się tętno koni wystawionych na działanie bodźca, ale konie z grupy badawczej wykazywały mniejsza reaktywność po 6 tygodniach. Wyniki sugerują przeciwlękowe działanie CBD (6).…”

Section: Potwierdzony Naukowo Zakres Działania Cbd U Koniunclassified

The application of cannabidiol in the treatment and health prevention of horses

NAWROT¹,

SOROKO-DUBROVINA²

2022

Medycyna Weterynaryjna

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Cannabidiol (CBD) is one of the cannabinoids found in Cannabis sativa L. The action of CBD in the body is similar to that of neurotransmitters, thanks to which it regulates most of the biochemical processes taking place in the body. Research on CBD properties in equine veterinary medicine has begun relatively recently. It has recently been proven to reduce inflammation, relieve pain, stabilize the nervous system, and have a calming effect. Human studies suggest that, due to its effects on the endocannabinoid system, CBD will have a number of positive effects on equine homeostasis. Current research is focused on determining appropriate CBD doses for desirable therapeutic or heeling effects. The results of studies carried out so far have confirmed the effectiveness of CBD, which may lead to further research on the use of CBD in the treatment and health prevention of horses.

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“…Studies conducted in mice and horses have shown that CBD reduces the production of inflammatory cytokines such as tumor necrosis factor-α (TNFα), which may help reduce inflammation in various body tissues or may have a calming effect and lessen anxiety in horses [1,2]. Horses receiving 40 g of a pelleted CBD supplement containing 100 mg of CBD over 6 weeks were less reactive to a novel stimulus compared to a control group; however, heart rates were not different and blood serum was not evaluated [3].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of an Oral Supplemental Cannabidiol Product for Acceptability and Performance in Mature Horses

Leise

Leatherwood

Paris

et al. 2023

Animals

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Thirty stock type geldings (15 ± 3 years; 556 ± 63 kg BW) were used in a randomized complete design over 28 days to determine the influence of cannabidiol (CBD) oil supplementation levels on body weight, body condition, and blood chemistry. Horses were randomly assigned to one of three dietary treatments (n = 10 per treatment) formulated with canola oil to provide 1.50 mg CBD/kg BW (TRTA), 0.75 mg CBD/kg BW (TRTB), or 0.00 mg CBD/kg BW (canola oil; CTRL). Treatments were top-dressed onto concentrate and individually administered twice daily. Horses were maintained in adjacent dry lots and received coastal bermudagrass hay ad libitum. Body weight and body condition scores (BCS) were obtained every 14 days. On day 0 and 28, blood was collected via jugular venipuncture and serum was harvested to perform a blood chemistry panel and drugs of abuse screening at the Texas Veterinary Medical Diagnostic Laboratory. Data were analyzed using PROC MIXED of SAS (v9.4), and the model included treatment, time, and the treatment × time interaction, and linear and quadratic orthogonal polynomial contrasts to partition sum of squares. Analysis of composited treatment samples revealed lower CBD concentrations than indicated from initial testing by the manufacturer (0.13 mg CBD/kg in TRTA; 0.12 mg CBD/kg in TRTB). At this level of supplementation, canola-based CBD oil was well-accepted by mature horses, banned substances were not detectable in blood, and blood chemistry parameters were not adversely affected as a result of supplementation. More research is warranted to describe the discrepancy between formulated levels compared to tested levels of CBD in the canola-based supplement.

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The effects of pelleted cannabidiol supplementation on heart rate and reaction scores in horses

Cited by 14 publications

References 28 publications

The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse

The use of cannabidiol as a novel treatment for oral stereotypic behaviour (crib-biting) in a horse

The application of cannabidiol in the treatment and health prevention of horses

Evaluation of an Oral Supplemental Cannabidiol Product for Acceptability and Performance in Mature Horses

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