The effects of placental transfusion on mothers

Chiruvolu, Arpitha; Estes, Emily; Stanzo, Karen; Desai, Sujata; Cornelius, Brandon C

doi:10.1080/14767058.2022.2032636

Cited by 7 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After removing duplicates, the articles were screened according to the inclusion and exclusion criteria yielding 398 for full-text review. Finally, 21 studies involving 23,330 pregnant patients met the eligibility criteria and were included in this study (4,(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39). The PRISMA ow chart (Figure S1) illustrates the details of the study selection process.…”

Section: Study Selectionmentioning

confidence: 99%

“…PPH was reported in twenty studies (4,(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(37)(38)(39). Incidence of PPH for vaginal delivery and CS was found to be 10.9% (95% CI: -0.017, 0.235, I 2 = 96%, n = 84) and 27.0% (95% CI: 0.180, 0.359, I 2 = 99%, n = 1226) respectively (Figs.…”

Section: Post-partum Haemorrhagementioning

confidence: 99%

“…Eleven studies reported birth weight with a mean weight of 2451.1 ± 499.0 g (4,20,22,23,26,29,30,(33)(34)(35)39). Prevalence of term deliveries and pre-term deliveries was found to be 47.3% (95% CI: -0.073, 1.020, I 2 = 100%, n = 6589) and 23.2% (95% CI: 0.057, 0.408, I 2 = 100%, n = 2977) respectively (Figs.…”

Section: Neonatal Outcomesmentioning

confidence: 99%

See 2 more Smart Citations

Twin Pregnancy and Postpartum Haemorrhage: A Systematic Review and Meta-analysis

Abdulsalam,

Bourdakos,

Burns

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Postpartum haemorrhage (PPH) continues to stand as the primary cause of maternal morbidity and mortality post-delivery, with twin pregnancies carrying a heightened risk of PPH compared to singleton deliveries. Objectives To investigate the incidence of primary PPH among twin pregnancies whilst evaluating the possible association between maternal and peripartum characteristics, considering the lack of a strong guideline on the risk stratification of PPH in such cases. Methods A literature search was conducted using data from PubMed, EMBASE, Cochrane, Scopus, and Web of Science. The search aimed to identify studies concerning mothers with twin pregnancies and postpartum haemorrhage (PPH) from the inception of each respective database to June 8th, 2023. Pooled means and proportions were analyzed using the generic inverse variance method. This review was registered prospectively with PROSPERO (CRD42023427192) Results A total of 21 studies involving 23,330 twin pregnant patients were included. Incidence of PPH for vaginal delivery and Caesarean delivery (CS) was found to be 10.9% (95% CI: -0.017, 0.235, I2 = 96%) and 27.0% (95% CI: 0.180, 0.359, I2 = 99%) respectively. In vitro fertilization (IVF) was the most common conception method at 62.0% (95% CI: 0.448, 0.792, I2 = 100%) with 81.1% (95% CI: 0.708, 0.915, I2 = 100%) of twins being dichorionic diamniotic. Conclusion This meta-analysis demonstrated more than one in ten vaginal deliveries and over one in four cesarean sections result in PPH for twin pregnancies. IVF is the predominant method of conception in this patient group and seems to contribute to subsequent PPH risk in specific mothers. While preliminary, these findings underscore the necessity for further well-designed and high-quality studies to validate these results.

show abstract

Section: Study Selectionmentioning

confidence: 99%

Section: Post-partum Haemorrhagementioning

confidence: 99%

See 1 more Smart Citation

Twin Pregnancy and Postpartum Haemorrhage: A Systematic Review and Meta-analysis

Abdulsalam,

Bourdakos,

Burns

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…The risk of excessive maternal bleeding from incision site while allowing for placental transfusion must be weighed against the bene ts of DCC for the infant (41). However, studies have found no difference in severe maternal haemorrhage (> 1000 ml) with DCC or physiology-based cord clamping (PBCC) during CS (32,(45)(46)(47).…”

Section: Introductionmentioning

confidence: 99%

Extra-uterine placental transfusion and intact-cord stabilisation of infants in caesarean sections: An intervention development and pilot-study (INTACT-1)

Sæther,

Andersson,

Bjellmo

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Keeping the umbilical cord intact the first minutes after delivery is beneficial for both term and preterm infants. However, this may be challenging in caesarean sections (CS) due to lack of mobile resuscitation equipment, maintenance of sterility or concern for excessive maternal blood loss. The objective of this study was to develop and pilot-test extra-uterine placental transfusion and intact-cord stabilisation of infants in CS. Methods: The intervention development process (phase 1) covered: A) placenta delivery without cord clamping, B) intact-cord stabilisation of the infant and C) physiology-based cord clamping. Different scenarios were tested through in-situ simulation and adjusted through multiple feedback rounds. The involved staff were trained prior to pilot-testing (phase 2). Women having a CS in regional anaesthesia, expecting a term or near-term singleton infant were included in the pilot-study after written consent. Primary outcome was the proportion of successfully completed interventions. For assessment of safety, maternal estimated intraoperative blood loss, infant 5-minute Apgar scores and infant rectal temperature during stabilisation were compared to pre-defined accept criteria. Dry-electrode ECG (NeoBeat™) was used for early detection of infant heartrate. Any respiratory support was registered. Early skin-to-skin contact between mother and infant was attempted for vigorous infants. Results: A detailed intervention protocol was developed and tested. Twenty-nine mother-infant-dyads were included in the pilot study. Gestational age ranged from 37 to 42 weeks. The intervention was successfully completed in 90 % of the cases, of which 31 % were planned CS. Median (SD) infant heart rates at one and five minutes were 159 (32) and 168 (21) beats per minute respectively. Eight infants (28%) had intact-cord respiratory support. One infant (3.5%) had a 5-minute Apgar score < 7 and three infants (10%) had rectal temperatures below 36.5°C during the first 10-15 minutes after birth. Three mothers (10%) had estimated intraoperative blood loss > 1000 ml Conclusion: Extra-uterine placental transfusion to facilitate intact-cord stabilisation and physiology-based cord clamping for infants delivered by CS was feasible and safe according to predefined accept criteria. Further testing of this complex intervention in larger, comparative studies is warranted. Trial registration: Regional Committee for Medical Research Ethics Central Norway (REK-Midt), #399101

show abstract