Research has shown that songs with prosocial lyrics can enhance individual prosociality. Building on the general learning model (GLM), this study demonstrated, through real-world charitable organizations, how songs with prosocial lyrics influence helping behavior that uses time as a currency. In Study 1, participants were randomly assigned to conditions of prosocial songs, prosocial lyrics, or neutral songs, and they were instructed to complete an online charity task. The results indicated that compared to the neutral songs, participants listening to prosocial songs and lyrics spent more time donating rice to the United Nations World Food Programme. This effect was replicated in Study 2, employing different media exposure from Study 1 (i.e., listening to background music). Furthermore, investigations into the underlying mechanisms revealed that this effect was mediated by interpersonal empathy. In summary, current findings suggest that songs with prosocial lyrics increase interpersonal empathy, subsequently influencing people’s online charitable donation behaviors in daily life.