The Effects of Public Access Defibrillation on Survival After Out-of-Hospital Cardiac Arrest

Baekgaard, Josefine S.; Viereck, Søren; Møller, Thea Palsgaard; Ersbøll, Annette Kjær; Lippert, Freddy; Folke, Fredrik

doi:10.1161/circulationaha.117.029067

Cited by 156 publications

(90 citation statements)

References 66 publications

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“…Cardiopulmonary resuscitation (CPR) requires the aid of general citizens, and in December 1990, the international standardized guidelines regarding out‐of‐hospital cardiac arrest (OHCA) were established . Concerning the Utstein‐style guidelines worldwide, several elements have been found to be associated with the prognosis of OHCAs, including a witnessed arrest by bystanders, bystander CPR, automatic external defibrillator (AED) use, and an initial shockable rhythm . In Japan, Osaka prefecture first introduced the guidelines in 1998.…”

Section: Introductionmentioning

confidence: 99%

Basic life support by citizens in Kawasaki City, Japan – a descriptive epidemiological study of out‐of‐hospital cardiac arrest patients

Shirakawa

Takebayashi

Kanao

et al. 2019

Acute Medicine & Surgery

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Aim To better understand the current status and barriers to making basic life support a common practice among the citizens of Kawasaki City, Japan. Method We extracted data according to the Utstein‐style guidelines specifically regarding out‐of‐hospital cardiac arrests (OHCAs) of cardiac etiology. The items were as follows: (i) OHCA witnessed by a citizen, (ii) the victim received bystander cardiopulmonary resuscitation (CPR), (iii) an automatic external defibrillator was used by the witness. We compared the rate of each item and the 1‐month survival rates with the national average in Japan. We further divided Kawasaki City into three areas and compared each item. We also examined the rate of bystander CPR in each time period and location. Statistical analysis was carried out using the χ2‐test and Fisher's test. Results The 1‐month survival rates did not differ significantly from the national average for cases meeting conditions (i)–(iii): (i) 14.0% versus 13.3%, (ii) 19.1% versus 16.4%, (iii) 71.4% versus 53.3%, respectively. However, the rate of condition (i) was significantly lower (47.5% versus 55. 8%, P = 0.01). The rate of condition (ii) was higher in the northern area of Kawasaki City, as well as in a location other than the home in the daytime. The rate of condition (ii) was low in the home. Conclusions Although the 1‐month survival rates of OHCAs witnessed by citizens in Kawasaki City did not differ significantly from the national average, the low rate of bystander CPR was notable, especially in the southern and middle areas of the city and when the location was in the home, which implies that basic life support knowledge should be spread to these areas.

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Section: Introductionmentioning

confidence: 99%

Basic life support by citizens in Kawasaki City, Japan – a descriptive epidemiological study of out‐of‐hospital cardiac arrest patients

Shirakawa

Takebayashi

Kanao

et al. 2019

Acute Medicine & Surgery

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“…There has been keen interest in determining how to improve treatment of out-of-hospital cardiac arrest, and to this end, Baekgaard et al 24 investigated the impact of public access defibrillation via an automated external defibrillator (AED) on survival after out-ofhospital cardiac arrest in their systematic review. The overall survival to hospital discharge after out-of-hospital cardiac arrest treated by public access defibrillation showed median survival of 40%, but the highest survival was seen in the group who received public access defibrillation from nondispatched lay first responders.…”

Section: Resuscitation and Response To Cardiac Arrestmentioning

confidence: 99%

Year in Review in Cardiac Electrophysiology

Tzou

Hussein

Madhavan

et al. 2018

Circ: Arrhythmia and Electrophysiology

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1 In the past year, there have been key advances in our understanding of arrhythmia mechanisms and diagnosis and important new therapies. We have seen advances in basic cardiac electrophysiology with demonstration of optogenetic targeting of atrial fibrillation (AF) rotors, induced pluripotent stem cell-based biological pacemakers, small-conductance Ca 2+ -activated K + (SK) channels as targets for AF treatment, and reductions in inward rectifier potassium current in promoting ventricular fibrillation. Hand-held ECG devices and implantable loop recorders have been shown to detect subclinical AF. Catheter ablation of AF in patients with left ventricular dysfunction improves outcomes compared with medical therapy. Both hybrid thoracoscopic surgical and catheter ablation procedures and off-pump surgery for AF have demonstrated efficacy. Anticoagulation with uninterrupted dabigatran had a lower major bleeding rate compared with uninterrupted warfarin after AF ablation. Studies have examined optimizing access to automatic external defibrillators by identifying optimal locations for placement and possibility of using a drone delivery network. In long-QT syndrome, there are advances in understanding of ECG predictors of arrhythmic events, the role of the role of gene variants in conferring arrhythmic risk, and effect of age and sex on QTc interval. There are numerous advances in the treatment of ventricular tachycardia, including noninvasive cardiac radiation. Catheter ablation and implantable devices continue to demonstrate effectiveness in patients with congenital heart disease.In the past year, there have been numerous ground-breaking discoveries and observations that illustrate the vibrancy and promise of our field. In this review, we have tried to capture articles published in the year 2017 of particular interest to cardiac electrophysiologists. Although we have focused on articles from our journal, we have captured many of the most impactful articles in numerous other journals. We apologize for omitting a large number of other important articles that cannot be included in this review because of space limitations. We have placed some of these in our Data Supplement. BASIC ELECTROPHYSIOLOGY BradyarrhythmiasThe search for new biological therapies for bradycardia met with recent progress as human keratinocytes genetically reprogrammed into electrically unstable cardiomyocytes were shown to persist and provide continued catecholaminergic-responsive pacing for 13 weeks after subepicardial injection into immunosuppressed dogs at the time of atrioventricular (AV) node ablation.1 Although only 40% to 80% of the beats matched the site of cell injection, this is first study to test a human induced pluripotent stem cell-based biological pacemaker in a large animal model of heart block and represents an important step forward in biological pacing.

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“…Furthermore, ensuring the availability of automated electrical defibrillators in public places should be encouraged as these may be of benefit in certain situations. 14,21 In Oman, there is a well-established EMS system in place with fully trained and equipped paramedics who can administer CPR if required. 22 Moreover, most people in Oman live in the governorate of Muscat, a region with excellent EMS coverage.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology, Outcomes and Coronary Angiography Findings of Patients Following Out-of-Hospital Cardiac Arrest: A single-centre experience from Oman

Nadar

Mujtaba

Al-Hadi

et al. 2018

Sultan Qaboos Univ Med J

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The Effects of Public Access Defibrillation on Survival After Out-of-Hospital Cardiac Arrest

Cited by 156 publications

References 66 publications

Basic life support by citizens in Kawasaki City, Japan – a descriptive epidemiological study of out‐of‐hospital cardiac arrest patients

Basic life support by citizens in Kawasaki City, Japan – a descriptive epidemiological study of out‐of‐hospital cardiac arrest patients

Year in Review in Cardiac Electrophysiology

Epidemiology, Outcomes and Coronary Angiography Findings of Patients Following Out-of-Hospital Cardiac Arrest: A single-centre experience from Oman

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