The effects of short term statin treatment on left ventricular function and inflammatory markers in patients with chronic heart failure

Mechanism of the Protective Effect of Yulangsan Flavonoid on Myocardial Ischemia/Reperfusion Injury in Rats

“…Moreover, when the cell membrane becomes permeable, a variety of intracellular enzymes are released into the blood during MI/RI, such as CK, CK-MB, LDH and LDH1. These enzymes are considered diagnostic markers of myocardial tissue damage [29,30,31]. Our research showed a significant elevation in the levels of CK, CK-MB, LDH and LDH1 in the model group and demonstrated that pretreatment with YLSF decreased the levels of these enzymes.…”

Costarring Statins With ARBs

“…Although the present study, 7 as well as previous studies, 5, 6 show a remarkable reduction in plasma BNP levels and a substantial recovery of cardiac function in such small study populations, they are hardly reflected in the large clinical trials, which have been mostly negative for drastic changes in plasma BNP level or overall primary outcomes. 12 One reason for the discrepancy is that the patients' characteristics and group composition would be different from those in the practical large cohorts, as was pointed out in the report from the J-CARE-GENERAL study.…”

Efekty leczenia atorwastatyną chorych w średnim wieku z zaawansowaną kardiomiopatią rozstrzeniową — prospektywne randomizowane badanie jednoośrodkowe

“…Gurgun et al [16] evaluated the effect of 12-week 80 mg fluvastatin therapy on the levels of inflammatory cytokines and left ventricular function in patients with DCM and heart failure due to coronary artery disease, with 20 patients recruited into each study group. The study showed a significant improvement of left ventricular function in both patients with DCM (LVEF increase from 30 ± 5% to 33 ± 5%, P = 0.001) and those with heart failure due to coronary artery disease (LVEF increase from 29 ± 4% to 31 ± 5%, P = 0.01).…”