This paper shows that a split-fuel-injection strategy can achieve robust, near-zero smoke and nitrogen oxide emissions at reduced exhaust gas recirculation levels under low-temperature combustion conditions. The overall objective of the work was to investigate the sensitivity (in terms of the engine emissions and the fuel economy) of a 50:50 (by mass) split-injection strategy to variations in the key engine operating parameters. Experiments were performed at operating conditions corresponding to a gross indicated mean effective pressure of 500 kPa at an engine speed of 1500 r/min in a 0.51 l single-cylinder high-speed direct-injection diesel engine. The paper presents the effects of different relative fuel injection timings at a variable intake oxygen mass fraction (10.5% and 12%) at a constant intake pressure (120 kPa, absolute) on the smoke, total hydrocarbon and carbon monoxide emissions with the split-main-injection strategy. The effects of a variable fuel injection pressure (90 MPa and 110 MPa) on diesel low-temperature combustion with split injection are also reported, as are the effect of an increased intake pressure (150 kPa, absolute). The combined effects of the operating parameters and the fuel injection timing on the smoke, nitrogen oxide, total hydrocarbon and carbon monoxide emissions and the gross indicated specific fuel consumption are described. For selected operating conditions, the cycle-resolved spray and combustion processes are visualized together with the flame temperature measurement using two-colour optical pyrometry to understand the combustion phenomena occurring in the split-injection strategy. The results of the optical studies show that different low-temperature combustion operating conditions producing similarly low levels of ‘engine-out’ smoke emissions have substantially different histories of soot formation and soot oxidation. An increase in the intake oxygen mass fraction reduced the total hydrocarbon emissions and the gross indicated specific fuel consumption at a given intake pressure, while a higher intake pressure reduced them further. Although significant soot formation took place from the second injection event, the majority of the soot was subsequently oxidized because of a slightly higher flame temperature and slightly higher oxygen concentration than in single-injection high-exhaust-gas-recirculation low-temperature combustion. A higher injection pressure did not have any significant effect on the emissions and the gross indicated specific fuel consumption.