“…Such evidence exists for nearly all surgical subspecialties, and within the subspecialties for complex, as well as simpler, interventions (see also Table 1). In visceral surgery, among others, cost savings have been shown for colorectal surgery [14][15][16], pancreaticoduodenectomy [17], hepaticojejunostomy [18], oesophagectomy [19], inguinal hernia repair [20], appendectomy [21][22][23], thyroidectomy [24], parathyreoidectomy [25] and several laparoscopic [26] and bariatric procedures [27]. Furthermore, treatment with clinical pathways leads to cost reduction in liver [28] and kidney transplantation [29].…”