The Effects of the Ingestion of Amino Acid on Gastric Secretion, with Particular Reference to L-Lysine Monohydrochloride

Sackler, Arthur M.; Sophian, Lawrence H.

doi:10.1093/ajcp/28.3.258

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Journal Of the American College Of Nutrition1

Human Studies1

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1997

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Cited by 7 publications

(2 citation statements)

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“…Sackler and Sophian reported that when adult volunteers were given test meals of bread and water, with and without 5 g of LMH, treatment produced a significant increase in gastric secretion of hydrochloric acid and pepsin, particularly the latter [103,104] while similar treatment with arginine monohydrochloride had no significant effect [105]. This, or a similar phenomenon, might be involved in the effect of lysine supplementation on growth of poorly thriving infants.…”

Section: Journal Of the American College Of Nutritionmentioning

confidence: 99%

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The metabolic roles, pharmacology, and toxicology of lysine.

Flodin

1997

Journal of the American College of Nutrition

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L-lysine monohydrochloride (LMH) is widely available to the public as a nonprescription oral supplement. Most of the pharmaceutical-grade product is used as a suppressant of recurrent herpes simplex infections. Recent publications indicate the possibility of other therapeutic uses, e.g., in cardiovascular disease and osteoporosis. These and other potential applications are surveyed and evaluated in this review with suggestions for further study. Data on toxicity are reviewed and recommendations made regarding safety of chronic dosage levels.

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Section: Journal Of the American College Of Nutritionmentioning

confidence: 99%

“…Arginine monohydrochloride administered in the same way did not produce these effects. Both AAs were well tolerated [103][104][105].…”

Section: Human Studiesmentioning

confidence: 99%