The effects of thyroidectomy on the wheel running activity of female rats

Stern, Jeffrey J.

doi:10.1016/0031-9384(70)90040-5

Cited by 10 publications

(1 citation statement)

References 4 publications

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“…The behavioral ind icators (ambulation, rea ring) do not evid ence tha t th e ani mals arc hyp othyroid, since the tradition al view ha s been tha t hypoth yroidism is acco m pa nied by lo w mot or activit y (Ri chter, 193 3 ;Hall & Lind say, 1938 ;Rrody , 1941Rrody , , 1942Stern , 1970) as me asured by the revolvin g-drum technique. Other reports (F euer & Broadhurst.…”

Section: Discussionmentioning

confidence: 99%

Effects of neonatal thyroxine stimulation on adult open-field behavior and thyroid activity in rats

Sjödén

Söderberg

1976

Psychobiology

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Three experiments are reported in which small groups of rats, given either thyroxine (T4) or triiodothyronine (T3) in large doses on Day 3 or Day 4 after birth, were tested in an open-field situation as adults. Ambulation and rearing were significantly increased by neonatal thyroid hormone treatment in both male and female rats. The effects were more pronounced among males than among females and were reduced by adult handling in the female group. With advancing age, hormone-treated rats showed a progressively lower body weight than controls. No consistent effect on thyroid uptake of radioiodine was noticed. The results are discussed with respect to possible implications for the reported adult learning deficit s in rats treated in a comparable manner.

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Section: Discussionmentioning

confidence: 99%