The most important task at all stages of development of modern agriculture is to increase the yield and quality of grain. Plant growth regulators can play a big role in this. In this paper, the influence of winter wheat seed treatment with Polaris fungicide and the use of Melafen growth regulator in winter wheat crops in the conditions of the Ufa district of the Republic of Bashkortostan is considered. Treatment of seeds with fungicide Polaris in combination with preparations for crop care provided yield at the level of 41.8-61.5 centner/ha. The use of Melafen in the experiment of growth regulator in the conditions of the Ufa district of the Republic of Bashkortostan provided an increase in crop yield to 59.2-63.7 centner/ha or by 30.3-40.4%, depending on the applied processing scheme. Due to the fact that the group of quality-all options correspond to the 2 group of quality or grain 3-5 class, the assessment of the quality of winter wheat grain shows that in the experiment the quality of grain of all options corresponds to the 3 commodity class.