The effects of vitamin E supplementation on sperm parameters, chromatin integrity, and gene expression before and after freezing in aged mice
Sadegh Zarei,
Farnoosh Molavi,
Farzaneh Abbas Abasnezhad
et al.
Abstract:Objective: Some age-related testicular changes, such as Sertoli cell vacuolization and blood–testis barrier breakdown, reduce total sperm production and male fertility. Therefore, this study investigated the effect of vitamin E on restoring testicular function in aged mice. Sperm cryo-resistance was also assessed. Methods: Twenty-eight 48-week-old male Naval Medical Research Institute mice were divided into four groups for a daily gavage of vitamin E: the control group received distilled water, while the three… Show more
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