The Effects of White Tea (Camellia Sinensis) and Infliximab Against Cisplatin- Induced Testicular Damage via Oxidative Stress and Apoptosis

Cakıroglu, Senay; Mercantepe, Tolga; Tumkaya, Levent; Uydu, Huseyin Avni; Topcu, Atilla; Atak, Mehtap

doi:10.4067/s0717-95022023000501537

Int. J. Morphol.

2023

DOI: 10.4067/s0717-95022023000501537

|View full text |Cite

The Effects of White Tea (Camellia Sinensis) and Infliximab Against Cisplatin- Induced Testicular Damage via Oxidative Stress and Apoptosis

Senay Cakıroglu,

Tolga Mercantepe,

Levent Tumkaya

et al.

Abstract: The effects of white tea (Camellia sinensis) and infliximab against cisplatin-induced testicular damage via oxidative stress and apoptosis.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet

Ciftel,

Klisic,

Ciftel

et al. 2024

Life

View full text Add to dashboard Cite

High-fat diets have detrimental health impacts that increase the likelihood of developing obesity and metabolic syndrome. This study aimed to examine the potential antioxidant and anti-inflammatory effects of orlistat and white tea in rats fed a high-fat diet. Thirty-two rats were randomized into four groups: control (standard diet), HFD (high-fat diet), HFD+Orlistat (high-fat diet+orlistat), and HFD+WT (high-fat diet+white tea extract). A significant increase in malondialdehyde (MDA) levels and a decrease in total thiol (TT) levels were detected in the HFD group (p < 0.001). On the other hand, a decrease in the MDA level (p < 0.001) and an increase in the TT level were observed in the orlistat and white tea groups compared with those in the HFD group (p < 0.001). Histopathological examinations revealed that, compared with the HFD alone, orlistat and white tea reduced fat accumulation, prevented degenerative changes in hepatocytes, and decreased the histopathological damage score (p = 0.001). Immunohistochemical examinations of nuclear factor-kappa B (NF-kB/p65) revealed that compared with the HFD, orlistat and white tea reduced immunopositivity (p = 0.001). White tea decreases lipid peroxidation and oxidative stress. Both white tea and orlistat decreased fat formation and inflammation in the liver and regulated inflammation by reducing Nf-kB positivity. Nevertheless, further research is needed to assess their impact on human subjects.

show abstract

Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet

Ciftel,

Klisic,

Ciftel

et al. 2024

Life

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The Effects of White Tea (Camellia Sinensis) and Infliximab Against Cisplatin- Induced Testicular Damage via Oxidative Stress and Apoptosis

Abstract: The effects of white tea (Camellia sinensis) and infliximab against cisplatin-induced testicular damage via oxidative stress and apoptosis.

Cited by 1 publication

References 53 publications

Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet

Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet

Contact Info

Product

Resources

About