The effects of whole‐body vibration amplitude on glucose metabolism, inflammation, and skeletal muscle oxygenation

Abstract

Whole‐body vibration (WBV) is an exercise mimetic that elicits beneficial metabolic effects. This study aims to investigate the effects of WBV amplitude on metabolic, inflammatory, and muscle oxygenation responses. Forty women and men were assigned to a high (HI; n = 20, Age: 31 ± 6 y) or a low‐amplitude group (LO; n = 20, Age: 33 ± 6 y). Participants engaged in 10 cycles of WBV [1 cycle =1 min of vibration followed by 30 s of rest], while gastrocnemius muscle oxygen consumption (mVO2) was assessed using near‐infrared spectroscopy (NIRS). Blood samples were collected PRE, POST, 1H, 3Hs, and 24H post‐WBV and analyzed for insulin, glucose, and IL‐6. In the LO group, Homeostatic Model Assessment for Insulin Resistant (HOMA‐IR) at 3 h (0.7 ± 0.2) was significantly lower compared to PRE (1.1 ± 0.2; p = 0.018), POST (1.3 ± 0.3; p = 0.045), 1H (1.3 ± 0.3; p = 0.010), and 24H (1.4 ± 0.2; p < 0.001). In addition, at 24H, HOMA‐IR was significantly lower in the LO when compared to the HI group (LO: 1.4 ± 0.2 vs. HI: 2.2 ± 0.4; p = 0.030). mVO2 was higher (p = 0.003) in the LO (0.93 ± 0.29 ml/min/100 ml) when compared to the HI group (0.63 ± 0.28 ml/min/100 ml). IL‐6 at 3H (LO: 13.2 ± 2.7 vs. HI: 19.6 ± 4.0 pg·ml−1; p = 0.045) and 24H (LO: 4.2 ± 1.1 vs. HI: 12.5 ± 3.1 pg·ml−1; p = 0.016) was greater in the HI compared to the LO group. These findings indicate that low‐amplitude WBV provides greater metabolic benefits compared to high‐amplitude WBV.

Assessment of cardiovascular risk, heart rate variability, and functionality in the late postoperative period of bariatric surgery submitted to whole-body vibration exercise: A case report

“…It was also found that after 30 minutes of rest after WBV, there was a reduction of 21.8% in the acute phase and we noticed an increase in glycemia of 3.1% in the chronic phase. This result was similar to that found by Sanni et al [21], as the low-amplitude EWBV contributed to a more favorable improvement in glucose metabolism when compared to high-amplitude WBV.…”

“…The studied individual has risk factors for cardiovascular diseases, obesity, and a sedentary lifestyle. Physical inactivity increases the relative risk of developing type 2 diabetes mellitus by up to 112% [21].…”

“…According to Sanni et al [21], WBV provides beneficial changes in glucose metabolism. Regarding the effect on capillary glycemia, we evaluated pre-WBV, at the 5th and 10th minutes, immediately after the intervention (15th minute) and 30 minutes after WBV.…”

Whole-body vibration as a passive alternative to exercise after myocardial damage in middle-aged female rats: Effects on the heart, the brain, and behavior

“…Exercise (Petersen and Pedersen, 2005 ) and WBV (Jawed et al, 2020 ; Sanni et al, 2022 ) are associated with anti-inflammatory effects. This anti-inflammatory property may extend to neuroinflammation (Mee-Inta et al, 2019 ; Chen et al, 2022 ; Oroszi et al, 2022a ).…”

Non-Invasive Pulsatile Shear Stress Modifies Endothelial Activation; A Narrative Review

“…Sanni et al investigated the acute effects of WBV (HI = 88.7 ms 2 and LO =44.4 ms 2 , both at 30 Hz) in healthy volunteers. They report a higher muscle oxygen consumption in the LO compared to the HI group and an increase in IL-6 in both groups but a higher in the LO [ 165 ]. Rodriguez-Miguelez studied healthy elderly volunteers (70 years) who performed an 8-week training protocol on WBV.…”