Abstract:RationaleΔ9‐Tetrahydrocannabinol (THC) produces both aversive and rewarding effects in animal models. Given that the balance between a drug's affective properties is thought to underlie its abuse potential, it is important to consider these properties of THC and how they (and their balance) are impacted by various factors. In this context, previous studies have examined the effect of THC history on the aversive and rewarding effects of THC. However, such assessments have been made in different animals under di… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.