The efficacy and safety of a cream containing salicylic acid, lipohydroxy acid, nicotinamide and piroctone olamine combined with 5% Benzoyl Peroxide in the  treatment of acne vulgaris: a randomized controlled study

Li, W; Shen, Z; Zhang, Z; Zhang, W; Kerob, D; Cx, Li

doi:10.25251/skin.6.supp.88

Cited by 2 publications

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“…Salicylic acid facial mask gel continuously reduced the three evaluation indexes of oil secretion, number of pores, and volume of pores on the nose and chin, Li et al. also obtained significant improvements in pore density and sebum secretion in the efficacy trials of facial serum and facial mask containing salicylic acid [47]; however, the three evaluation indexes did not improve after applying arbutin and hexapeptide facial mask gel.…”

Section: Discussionmentioning

confidence: 99%

Preparation and efficacy verification of three‐dimensional printed partitioned multi‐effect precision‐care gel facial mask

Chen,

Liufu,

Zhang

et al. 2024

Intern J of Cosmetic Sci

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ObjectiveA partition multi‐effect precision‐care gel facial mask conforming to facial skin characteristics was prepared using three‐dimensional (3D) printing technology.MethodsFirst, the hydrogel matrix and humectant of a 3D‐printed gel for facial masks were screened, and three 3D‐printed gels of arbutin, hexapeptide, and salicylic acid were prepared with whitening, wrinkle removal, and oil control functions, respectively. Skin irritation tests were performed on the gels. Physicochemical properties such as pH, heat and cold tolerance were evaluated. The efficacy of three 3D‐printed gels was assessed by measuring melanin value, wrinkle depression score, and oil secretion. Finally, the facial mask model design and printing parameters were studied, and a partition multi‐effect precision‐care gel facial mask was printed in line with facial skin characteristics.ResultsFor the 3D‐printed facial mask, the gel prescription with 2% hydroxyethyl cellulose gel as matrix and 7% glycerol as humectant was the best. The prepared 3D‐printed gel did not irritate the human skin, and its physicochemical properties met the Chinese facial mask industry standard (QB/T2872‐2017). We showed that three types of 3D‐printed gels containing arbutin, hexapeptide, and salicylic acid could be applied to the corresponding parts of the face to solve different problems, such as facial skin dullness, wrinkles, and oil secretion. Therefore, according to facial physiological characteristics, the facial mask model was designed for the forehead and nasolabial fold, which needs to be anti‐wrinkled; the cheek, which needs to be whitened; and the nose and chin, which need oil control. The optimal printing parameters were 0.26 mm nozzle diameter, 90 mm/s printing speed, 30% filling density, 140% wire extrusion ratio, and 0.25 mm layer height. Different skin care effects can be achieved using a three‐nozzle printer to print arbutin, hexapeptide, or salicylic acid gel on the mask's forehead and nasolabial fold, cheek, and nose and chin, respectively.ConclusionThe 3D‐printed partition multi‐effect care gel facial mask prepared according to the skin features of different parts of the face can overcome the problem of the single skincare effect of the mass‐produced facial masks.

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Section: Discussionmentioning

confidence: 99%

Preparation and efficacy verification of three‐dimensional printed partitioned multi‐effect precision‐care gel facial mask

Chen,

Liufu,

Zhang

et al. 2024

Intern J of Cosmetic Sci

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“…These observations are consistent with previous research on the efficacy of salicylic acid, lipohydroxy acid and niacinamide in treating PIH or pigmentary disorders, while suggesting potential benefits from the other components in the DC formula. 5,6 For instance, niacinamide works by inhibiting melanosome transfer from melanocytes to keratinocytes. 6 Figure 1 displays an example of significant improvement in PIH after the 8-week treatment.…”

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confidence: 99%

Efficacy of a dermocosmetic skin care regimen in reducing acne‐associated post‐inflammatory hyperpigmentation in subjects with phototypes IV to VI

Benzaquen,

Salah,

Nioré

et al. 2024

JEADV Clinical Practice

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The efficacy and safety of a cream containing salicylic acid, lipohydroxy acid, nicotinamide and piroctone olamine combined with 5% Benzoyl Peroxide in the treatment of acne vulgaris: a randomized controlled study

Cited by 2 publications

References 0 publications

Preparation and efficacy verification of three‐dimensional printed partitioned multi‐effect precision‐care gel facial mask

Preparation and efficacy verification of three‐dimensional printed partitioned multi‐effect precision‐care gel facial mask

Efficacy of a dermocosmetic skin care regimen in reducing acne‐associated post‐inflammatory hyperpigmentation in subjects with phototypes IV to VI

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