The efficacy and safety of colonoscopy preparation with oral sodium phosphate in elderly patients

Yakut, Mustafa; Çınar, Kubilay; Seven, Gülseren; Çetinkaya, Hülya; Bahar, Kadir

doi:10.4318/tjg.2010.0072

Cited by 13 publications

(11 citation statements)

References 26 publications

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“…During intestinal preparation, oral laxatives can stimulate the stomach and intestines, easily resulting in gastrointestinal symptoms, such as nausea, vomiting, and abdominal pain (20,21). The results suggest that PEG is less likely to trigger side reac-tions such as those previously mentioned than magnesium sulfate solution.…”

Section: Discussionmentioning

confidence: 82%

Enteral nutrition before bowel preparation improves the safety of colonoscopy in the elderly

Zhang¹,

Chen²,

Zhang³

et al. 2013

Turk J Gastroenterol

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Section: Discussionmentioning

confidence: 82%

Enteral nutrition before bowel preparation improves the safety of colonoscopy in the elderly

Zhang¹,

Chen²,

Zhang³

et al. 2013

Turk J Gastroenterol

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“…In addition, bowel preparation and fluid restriction applied during the operation may cause hyperphosphataemia, hyponatraemia, hypokalaemia and hypocalcaemia with acute tubular necrosis, metabolic acidosis and renal impairment in this group of patients (17)(18)(19).…”

Section: Discussionmentioning

confidence: 99%

Effects of Bowel Preparation and Fluid Restriction in Robot-Assisted Radical Prostatectomy Patients

Karaören¹,

Bakan²,

Yürük³

et al. 2015

Turk J Anesth Reanim

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Amaç: Robot yardımlı radikal prostatektomi (RYRP) ameliyatlarında preoperatif bağırsak hazırlığı ve intraoperatif sıvı kısıtlaması dehidratasyona ve elektrolit dengesizliğine neden olabilmektedir. Bu hastalarda yatış öncesi anestezi polikliniğinde "normal" olarak değerlendirilen labaratuvar değerleri anestezi uygulaması esnasın-da yanıltıcı olabilmekte ve hipokalsemi ve hipokalemiye bağlı kalp ritmi bozukluklarına, depolarizan blokta uzamaya ve anesteziden derlenmenin gecikmesine neden olabilmektedir. Biz çalışmamızda RYRP ameliyatlarında bağırsak temizliği ve sıvı kısıtlamasının preoperatif (T1) alınan labaratuvar değerleri ile ameliyat başlangıcın-da (T2) ve ameliyatın 6. saatinde (T3) alınan labaratuvar değerleri arasında bu tip yan etkilere yol açabilecek derecede farklılığa sebep olup olmadığını araştırmayı amaçladık.Yöntemler: American Society of Anesthesiologists (ASA) I-II 49 hasta uzerinde yaptığımız prospektif çalışmada hastaların bağırsak hazırlığı 12 saat içinde 2 defa rektal enema (NaP) ve tek doz oral soda (NaP) kullanılarak yapıldı. Ameliyat süresince 1 mL kg -1 h -1 %0,09 NaCl ve 1 mL kg -1 h -1 %6 HES 200/05 infüzyonları uygulandı.Bulgular: T2'de potasyum düzeyi T1 ve T3'e göre; T2 ve T3'teki kalsiyum düzeyi ise T1'e göre istatistiksel olarak anlamlı düşük saptandı. T3 kalsiyum değeri de T2'den anlamlı düşük, T3 kreatinin değeri ise T1 ile T2'den istatistiksel olarak yüksek saptandı.Sonuç: ASA I-II hasta grubunda yaptığımız çalışmamızda bağır-sak hazırlığı ve sıvı kısıtlamasına bağlı labaratuvar değerlerinde her ne kadar ciddi yükseliş ve düşüşler saptanmamış olsa da bu deği-şimler yüksek riskli ASA III-IV hastalarda önem taşıyabilir.Anahtar Kelimeler: Uzaktan operasyon (robotik), dehidratasyon, sıvı elektrolit imbalansı, barsak hazırlığı Objective: In Robot-assisted radical prostatectomy (RARP) patients, preoperative bowel preparation and intraoperative fluid restriction may cause dehydration and electrolyte imbalance. In these patients, laboratory results that are considered "normal" in the pre-anaesthesia clinic may be misleading, and cardiac arrhythmia due to hypokalaemia and hypocalcaemia, as well as problems, such as prolonged non-depolarising blockade and delayed recovery from anaesthesia, may be observed during anaesthesia practice. In this study, we aimed to determine these disturbances by comparing the preoperative (T1) laboratory values with those at the beginning of the operation (T2) and at the 6 th hour of the operation (T3) and values at discharge. Methods:This prospective study comprised 49 American Society of Anesthesiologists (ASA) I-II patients. Bowel preparation was made with a rectal enema (NaP) twice in 12 hours and with one single dose of oral laxative soda (NaP). During surgery, 1 mL kg -1 h -1 0.09% NaCl and 1 mL kg -1 h -1 6% HES 200/05 infusions were applied. Results:The potassium level at T2 was significantly lower than at T1 and T3. The calcium levels at T2 and T3 were significantly lower than at T1, and the level at T3 was significantly lower than at T2. The creatin...

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“…Gumurdulu et al showed that the risk of an increase in sodium and phosphate levels was mainly seen in older patients after taking oral phospho-soda as a precolonoscopic preparation regime (21). On the other hand, studies did not show high levels of phosphate and sodium at the fifth day after taking oral Fleet phosphosoda as a colonoscopic preparation regime (18). Likewise, Unal et al showed transient hyperphosphatemia and hypernatremia with the same regime (19).…”

Section: Discussionmentioning

confidence: 99%

What is the main target: a clearer colon with a sennoside-based regime, or adequate bowel cleansing before colonoscopy with a PEG-EL-based regime?

Altınbaş¹,

Yılmaz²,

Aktaş³

et al. 2015

Turk J Med Sci

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Background/aim: Even though polyethylene glycol-electrolyte lavage (PEG-EL)-based regimes have become the gold standard in recent years, to finish drinking 4 L of PEG-EL solution can be difficult. The quality of sennoside-based bowel-cleansing regimes used in Turkey has been known for some time. Therefore, we aimed to investigate the efficacy of both bowel-cleansing regimes. Materials and methods:Patients over 18 years old undergoing elective colonoscopic procedures between January and March 2011 were included in the study. The patients were divided into 2 groups; in Group 1, 91 patients were given sennoside a + b calcium 500 mg/250 mL (X-M solution, Yenişehir Laboratuarı, Ankara, Turkey), and in Group 2, 94 patients were given 4 L of PEG-EL (Golytely, Boston, MA, USA). Results:The mean age of the patients and the male distribution were similar in the 2 groups. Both inadequate bowel cleansing and the best cleansed bowels were seen in Group 1. The number of inadequate colonoscopies declined when using a whole bowel-cleansing regime from 24.5% to 19.3% in Group 2, but it did not decline in Group 1. Conclusion:The best bowel cleansing can be achieved with sennoside-based regimes, whereas a greater proportion of adequate results via colonoscopy were reached with the PEG-EL-based regimes.

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The efficacy and safety of colonoscopy preparation with oral sodium phosphate in elderly patients

Abstract: (abdominal pain, nausea, vomiting, dizziness, hypotension)

Cited by 13 publications

References 26 publications

Enteral nutrition before bowel preparation improves the safety of colonoscopy in the elderly

Enteral nutrition before bowel preparation improves the safety of colonoscopy in the elderly

Effects of Bowel Preparation and Fluid Restriction in Robot-Assisted Radical Prostatectomy Patients

What is the main target: a clearer colon with a sennoside-based regime, or adequate bowel cleansing before colonoscopy with a PEG-EL-based regime?

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