The Efficacy of a Didactic and Case-Based Pharmacogenomics Education Program on Improving the Knowledge and Confidence of Alberta Pharmacists

Hayashi, Meagan; Mahmoud, Sherif Hanafy; Hamdy, Dalia A.

doi:10.2147/pgpm.s348851

Cited by 6 publications

(5 citation statements)

References 54 publications

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“…Indeed, a study has shown that pharmacogenomics knowledge was significantly greater among pharmacists who were educated and trained about pharmacogenomics and counseled patients regarding their pharmacogenomics results [ 23 ]. Also, to assess the impact of continuing education programs, Hayashi et al [ 24 ] evaluated the effect of didactic, i.e., traditional teacher-based learning, and case-based studies-related programs via synchronous (virtual) and asynchronous (online self-study) environments on Canadian pharmacists' confidence in pharmacogenomics and their level of knowledge. It is noteworthy to mention that 88.9% of the participants were community pharmacists.…”

Section: Discussionmentioning

confidence: 99%

Investigation of community pharmacists’ knowledge and attitudes of pharmacogenomics testing: implication for improved pharmacogenomic testing practice

Ramadan,

Jarab,

Al Meslamani

2024

Hum Genomics

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Background Community pharmacists must be well-equipped to advance pharmacogenomics services. Nevertheless, limited data is available regarding pharmacists' knowledge and attitudes toward pharmacogenomics testing. The present study aimed to evaluate community pharmacists' knowledge and attitudes toward pharmacogenomics testing in the UAE. Methods In this cross-sectional study, a validated, online, self-administered survey, was randomly distributed to community pharmacists across the United Arab Emirates (UAE). Results The participants demonstrated poor knowledge about pharmacogenomic testing (median score < 8). Having 10–29 (Adjusted odds ration [AOR]: 0.038; 95% CI: 0.01–0.146, p = 0.001) and 30–49 (AOR: 0.097; 95% CI: 0.04–0.237, p = 0.001) patients per day was associated with poorer knowledge. Also, receiving 10–29 (AOR: 0.046; 95% CI: 0.005–0.401, p = 0.005), 30–49 (AOR: 0.025; 95% CI: 0.003–0.211, p = 0.001), and > 50 (AOR: 0.049; 95% CI: 0.005–0.458, p = 0.008) prescriptions decreased the odds of having good knowledge. Around half (43.9%) of the participants did not show a positive attitude toward pharmacogenomic testing (median score < 11). Having 30–49 patients per day (AOR: 5.351; 95% CI: 2.414–11.860, p = 0.001) increased the odds of good knowledge while receiving 10–29 (AOR: 0.133; 95% CI: 0.056–0.315, p = 0.001) and 30–49 (AOR: 0.111; 95% CI: 0.049–0.252, p = 0.001) prescriptions a day were associated with decreased odds of positive attitude toward the pharmacogenomics testing. Conclusions The findings indicate a lack of knowledge and less-than-ideal attitudes among community pharmacists regarding pharmacogenomics testing. Enhanced efforts focused on educational initiatives and training activities related to pharmacogenomics testing is needed. Additionally, reducing workload can facilitate better knowledge acquisition and help mitigate unfavorable attitudes.

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Section: Discussionmentioning

confidence: 99%

Investigation of community pharmacists’ knowledge and attitudes of pharmacogenomics testing: implication for improved pharmacogenomic testing practice

Ramadan,

Jarab,

Al Meslamani

2024

Hum Genomics

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“…In light of the increasing importance of biomarkers and pharmacogenomics in patient care, pharmacy schools have implemented courses on precision medicine in their curricula ( Nagy et al, 2020 ). Practice-based education programs have also proved effective, resulting in a significant increase in pharmacists' knowledge and competence in this area ( Hayashi et al, 2022 ).…”

Section: Role Of Oncology Pharmacists Advanced Practice Nurses and Ph...mentioning

confidence: 99%

The Advanced Practitioner’s Role in the Rapidly Evolving Landscape of Precision Medicine

C. Moore, PharmD, BCPS, BCOP, DPLA, FCCP,

S. Guinigundo, MSN, RN, CNP, ANP-BC

2023

JADPRO

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The advent of precision medicine targeting oncogenic mutations and other alterations has led to a paradigm shift in the treatment of many solid tumors and hematologic malignancies. For many of these agents, predictive biomarker testing is necessary to determine the presence of such alterations in order to select patients who are most likely to respond, and to avoid the use of ineffective and potentially harmful alternative therapy. Recent technological advances such as next-generation sequencing have facilitated the identification of targetable biomarkers in patients with cancer and thus help inform treatment decisions. Moreover, new molecular-guided therapies and associated predictive biomarkers continue to be discovered. For some cancer therapeutics, regulatory approval requires the use of a companion diagnostic to ensure proper patient selection. Advanced practitioners therefore need to be aware of current biomarker testing guidelines regarding who should be tested, how and when to test, and how these results can guide treatment decisions using molecular-based therapies. They should also recognize and address potential barriers and disparities in biomarker testing to ensure equitable care for all patients, and assist in educating patients and colleagues alike on the importance of testing and integration into clinical practice to enhance outcomes.

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“…27 Yet, some hesitate to share PGx information with other healthcare providers due to the lack of standardized PGx education currently incorporated into pharmacy programs. [28][29][30][31] Despite the advancement in high-quality PGx research, increased test and guideline availability, demonstrated feasibility and applicability of testing in pharmacy workflow, its widespread implementation in clinical pharmacy practice has remained limited. 22,27,32 To inform the future delivery of PGx education and clinical implementation, we aim to provide an overview of what is currently known regarding the knowledge, attitudes, perceptions, and confidence of pharmacists and pharmacy students toward PGx.…”

Section: Introductionmentioning

confidence: 99%

“…A recent scoping review reported the demonstrated feasibility of PGx testing and improved medication outcomes in pharmacy practice 27 . Yet, some hesitate to share PGx information with other healthcare providers due to the lack of standardized PGx education currently incorporated into pharmacy programs 28–31 …”

Section: Introductionmentioning

confidence: 99%

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Knowledge, perceptions, and attitudes toward pharmacogenomics among pharmacists and pharmacy students: A systematic review

Wondrasek,

Fryza,

Aziz

et al. 2024

Health Science Reports

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Background and AimsPharmacists have been recognized as one of the most qualified healthcare professionals in the clinical implementation of pharmacogenomics, yet its widespread implementation in clinical pharmacy practice has remained limited. The review aims to systematically investigate knowledge, perceptions, and attitudes toward pharmacogenomics among pharmacists and pharmacy students to inform the future delivery of pharmacogenomics education programs.MethodsPubMed, MEDLINE, Embase, Scopus, and the International Pharmaceutical Abstracts were searched up to May 17, 2022. Studies were selected if they included data on pharmacists' or pharmacy students' knowledge, perception, or attitude about pharmacogenomics and were published in a peer‐reviewed, English‐language journal with full‐text availability. Any published study not deemed original research was excluded. All included studies were critically appraised using the Center for Evidence‐Based Management's critical appraisal tools. The data were descriptively analyzed and presented based on pharmacists' and pharmacy students' knowledge/awareness, perception/attitudes toward pharmacogenomic (PGx), confidence in using or interpreting PGx testing results, and their desire to get further PGx education or their most preferred method of further education.ResultsA combined total of 12,430 pharmacists and pharmacy students from 26 countries are represented in the 52 included studies. Despite overwhelmingly positive attitudes and perceptions toward pharmacogenomics among pharmacists and pharmacy students, an overall lack of adequate knowledge and confidence was found. The review also found a strong desire for further pharmacogenomics education among pharmacists and pharmacy students.ConclusionPharmacists and pharmacy students have positive perceptions and attitudes toward pharmacogenomics, which is hindered by a lack of knowledge and confidence. However, inadequate control for confounders, limited representativeness of the studied population or region, and small sample sizes diminish the generalizability of the review results. Knowledge and confidence could be improved through enhanced delivery of pharmacogenomic courses within the pharmacy curriculum and continuing education programs.

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The Efficacy of a Didactic and Case-Based Pharmacogenomics Education Program on Improving the Knowledge and Confidence of Alberta Pharmacists

Cited by 6 publications

References 54 publications

Investigation of community pharmacists’ knowledge and attitudes of pharmacogenomics testing: implication for improved pharmacogenomic testing practice

Investigation of community pharmacists’ knowledge and attitudes of pharmacogenomics testing: implication for improved pharmacogenomic testing practice

The Advanced Practitioner’s Role in the Rapidly Evolving Landscape of Precision Medicine

Knowledge, perceptions, and attitudes toward pharmacogenomics among pharmacists and pharmacy students: A systematic review

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