The efficacy of calcium glycerophosphate in the prevention of food-related flares in interstitial cystitis

Bologna, Raymond; Gomelsky, Alex; Lukban, James; Tu, Le Mai; Holzberg, Adam S.; Whitmore, Kristene

doi:10.1016/s0090-4295(01)01070-6

Cited by 21 publications

(7 citation statements)

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“…Some supplements, such as calcium glycerophosphate (Prelief), vitamin D, fish oil and probiotics, were also considered to be helpful. Calcium glycerophosphate appears to reduce BPS symptoms in a patient whose symptoms are exacerbated by particular foods [ 34 ]. Tettamanti et al reported their findings from a population-based study demonstrating that tea and smoking were positively associated with BPS [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Complementary therapies for bladder pain syndrome: a systematic review

et al. 2015

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Introduction and hypothesisBladder pain syndrome is a difficult condition to treat. The purpose of this systematic review is to assess the effectiveness of various complementary therapies available for treatment.MethodsThis review was conducted in adherence with Preferred Reporting Items for Systematic Reviews. Citations were retrieved using a comprehensive database search (from inception to July 2014: CINAHL, Cochrane, EMBASE, Medline and SIGEL and grey literature). Studies that fulfilled the inclusion criteria were selected. Eligibility consisted of women with bladder pain syndrome, an intervention of alternative/complementary therapies and an outcome of improvement of symptoms. Information regarding study characteristics and primary outcomes was collated. The Cochrane risk of bias scale was used to evaluate the quality of the studies included.ResultsA total of 1,454 citations were identified, 11 studies fulfilled the inclusion criteria (4 randomised control trials [RCTs] and 7 prospective studies). The key interventions studied were acupuncture, relaxation therapy, physical therapy, hydrogen-rich therapy, diet and nitric oxide synthetase.ConclusionTherapies with the potential for benefit in patients with bladder pain syndrome are dietary management, acupuncture and physical therapy. These findings were obtained from small studies and hence caution is advised. Robustly designed multicentre RCTs on these complementary therapies are needed to guide patients and clinicians.

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Section: Discussionmentioning

confidence: 99%

Complementary therapies for bladder pain syndrome: a systematic review

et al. 2015

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“…This may demonstrate not only physicians' acceptance of diet therapy as mainstream PBS/IC treatment, but also their response to increased patient interest, their own interest, or their willingness to try CAM because traditional therapies have not been successful . A number of dietary supplements and herbs have been the subjects of research for PBS/IC treatment, including calcium glycerophosphate, L ‐arginine, Chinese herbs, and a quercetin‐containing combination . However, only one supplement, calcium glycerophosphate, was found to be helpful by a significant number of patients.…”

Section: Discussionmentioning

confidence: 99%

“…22 A number of dietary supplements and herbs have been the subjects of research for PBS/IC treatment, including calcium glycerophosphate, L-arginine, Chinese herbs, and a quercetin-containing combination. 3,[23][24][25][26] However, only one supplement, 24 calcium glycerophosphate, was found to be helpful by a significant number of patients. Herbal formulas have also been used as the treatment alternatives for PBS/IC.…”

Section: Discussionmentioning

confidence: 99%

Reduction of oxidative stress may play a role in the anti-inflammatory effect of the novel herbal formulation in a rat model of hydrochloric acid-induced cystitis

Bae

Kim

et al. 2013

Neurourol. Urodynam.

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“…sodium bicarbonate, or agents that neutralize acid in food, e.g. calcium glycerophosphate [19,20], might provide symptomatic relief. With the exception of cranberries, other acidic foods do not necessarily produce a change in urine pH or a corresponding change in the physiological state of the bladder [21].…”

Section: The Link Between Diet and Ic/bps Related Painmentioning

confidence: 99%

Diet and its role in interstitial cystitis/bladder pain syndrome (IC/BPS) and comorbid conditions

2012

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What ' s known on the subject? and What does the study add? Nearly 90% of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) report sensitivities to a wide variety of dietary comestibles. Current questionnaire-based literature suggests that citrus fruits, tomatoes, vitamin C, artifi cial sweeteners, coffee, tea, carbonated and alcoholic beverages, and spicy foods tend to exacerbate symptoms, while calcium glycerophosphate and sodium bicarbonate tend to improve symptoms. At present we recommend employing a controlled method to determine dietary sensitivities, such as an elimination diet, in order to identify sensitivities while at the same time maintain optimal nutritional intake.We review current literature with regard to diet ' s effect upon IC/BPS and common comorbidities (irritable bowel syndrome, fi bromyalgia, chronic fatigue syndrome, neuropathic pain, vulvodynia, and headache) with a focus upon questionnaire-based investigations. We discuss the pathologic mechanisms that may link diet and IC/BPS related-pain, concentrating upon specifi c comestibles such as acidic foods, foods high in potassium, caffeine, and alcohol.

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The efficacy of calcium glycerophosphate in the prevention of food-related flares in interstitial cystitis

Cited by 21 publications

References 0 publications

Complementary therapies for bladder pain syndrome: a systematic review

Complementary therapies for bladder pain syndrome: a systematic review

Reduction of oxidative stress may play a role in the anti-inflammatory effect of the novel herbal formulation in a rat model of hydrochloric acid-induced cystitis

Diet and its role in interstitial cystitis/bladder pain syndrome (IC/BPS) and comorbid conditions

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