The efficacy of dairy products fortified with nano-encapsulated vitamin D3 on physical and mental aspects of the health in obese subjects; the protocol of the SUVINA trial

Sharifan, Payam; Bagherniya, Mohammad; Bajgiran, Maryam Mohammadi; Safarian, Mohammad; Vatanparast, Hassan; Eslami, Saeid; Tayefi, Maryam; Khadem‐Rezaiyan, Majid; Baygan, Ali; Khoshakhlagh, Mahdieh; Ghazizadeh, Hamideh; Rashidmayvan, Mohammad; Palahang, Hanieh; Rezaie, Mitra; Ghayour‐Mobarhan, Majid

doi:10.1016/j.tmsr.2021.01.001

Cited by 8 publications

(8 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a clinical trial conducted on the African-American population, The link between vitamin D status and inflammation has been suggested not only in rheumatoid arthritis, but also in lupus, inflammatory bowel disease, and diabetes mellitus type 1, as well as in infections, cancer, transplant rejection, and cardiovascular diseases. 6,7,19,24,25,[28][29][30] Additionally, previous studies have shown that sufficient levels of vitamin D are necessary for normal brain neuropsychiatric function. 26,31 In fact, vitamin D insufficiency during embryonic development may alter brain development and lead to the appearance of mental health disorders such as psychosis 28,32 .…”

Section: Discussionmentioning

confidence: 99%

“…Vitamin D can also impact immune responses through the vitamin D receptor. In a clinical trial conducted on the African‐American population, The link between vitamin D status and inflammation has been suggested not only in rheumatoid arthritis, but also in lupus, inflammatory bowel disease, and diabetes mellitus type 1, as well as in infections, cancer, transplant rejection, and cardiovascular diseases 6,7,19,24,25,28–30 . Additionally, previous studies have shown that sufficient levels of vitamin D are necessary for normal brain neuropsychiatric function 26,31 .…”

Section: Discussionmentioning

confidence: 99%

“…This cross‐sectional study was conducted as part of the Survey of Ultraviolet Intake by Nutritional Approach study 19 . The inclusion criteria for the study were: age between 30 and 50, completion of the consent form and willingness to participate in the study, no intention of losing weight, and a waist circumference of more than 80 cm for women and more than 94 cm for men according to the International Diabetes Federation criteria 20 .…”

Section: Methodsmentioning

confidence: 99%

“…Also, hs-crp was measured using an autoanalyzer BT3000. 19 Whole blood collected in EDTA-containing tubes was used to measure hematological parameters, including platelet count, red blood cell distribution width (RDW), neutrophil and lymphocyte count, PLR, and NLR 17 using an automatic blood counter (Sysmex KX-21).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Association of dietary and blood inflammatory indicators with depression, anxiety, and stress in adults with vitamin D deficiency

Sharifan

Darroudi

Rafiee

et al. 2023

Int J Geriat Psychiatry

Self Cite

View full text Add to dashboard Cite

BackgroundThere is growing evidence that vitamin D may be related to mental health. The aim of the current study was to investigate the association of dietary and blood inflammatory factors with mental health disorders in subjects with vitamin D deficiency, shedding further light on the complex interplay of these conditions.MethodIn this cross‐sectional study, 306 subjects completed the validated Depression, Anxiety, and Stress Scale questionnaire to evaluate their depression, anxiety, and stress scores. Dietary inflammatory index (DII) and healthy eating index (HEI) were calculated using a validated 65‐item food frequency questionnaire. Blood samples were taken and vitamin D, cytokine, and hs‐CRP levels were measured using enzyme‐linked immunosorbent assay kits. Platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) were calculated using standard laboratory methods.ResultsThe subjects were divided into two groups based on their vitamin D levels: a vitamin D < 20 μg/dl group (N = 257) and a vitamin D ≥ 20 μg/dl group (N = 49). Between group analysis revealed that only DII (p = 0.015), platelet (p = 0.04), and hs‐CRP (p = 0.015) were significantly different. In adults with vitamin D levels below 20 μg/dl, NLR and DII were significantly higher in subjects with anxiety (p < 0.05), and this relationship remained significant only for NLR after adjusting for age and sex. Additionally, PLR and HEI were significantly different in depressed compared to non‐depressed subjects, and this association remained significant only for HEI after adjusting for age and sex.ConclusionIn subjects with vitamin D deficiency, increased levels of PLR, NLR, and DII were associated with depression and anxiety, while HEI was negatively associated with depression. These associations were not found in subjects with vitamin D levels ≥20 μg/dl.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Association of dietary and blood inflammatory indicators with depression, anxiety, and stress in adults with vitamin D deficiency

Sharifan

Darroudi

Rafiee

et al. 2023

Int J Geriat Psychiatry

Self Cite

View full text Add to dashboard Cite

show abstract

“…Data for this study were obtained from the survey of ultraviolet intake by nutritional approach (SUVINA) randomized control trial. The protocol of the SUVINA study has been published elsewhere 24 . This study was performed in the City of Mashhad in Iran from January 2019 to March 2019 for 10 weeks and comprised 306 adults (both case and control groups).…”

Section: Methodsmentioning

confidence: 99%

Factors determining the serum 25‐hydroxyvitamin D response to vitamin D supplementation: Data mining approach

et al. 2021

Self Cite

View full text Add to dashboard Cite

Vitamin D supplementation has been shown to prevent vitamin D deficiency, but various factors can affect the response to supplementation. Data mining is a statistical method for pulling out information from large databases. We aimed to evaluate the factors influencing serum 25-hydroxyvitamin D levels in response to supplementation of vitamin D using a random forest (RF) model. Data were extracted from the survey of ultraviolet intake by nutritional approach study. Vitamin D levels were measured at baseline and at the end of study to evaluate the responsiveness. We examined the relationship between 76 potential influencing factors on vitamin D response using RF. We found several features that were highly correlated to the serum vitamin D response to supplementation by RF including anthropometric factors (body mass index [BMI], free fat mass [FFM], fat percentage, waist-to-hip ratio [WHR]), liver function tests (serum gamma-glutamyl transferase [GGT], total bilirubin, total protein), hematological parameters (mean corpuscular volume [MCV], mean corpuscular hemoglobin concentration [MCHC], hematocrit), and measurement of insulin sensitivity (homeostatic model assessment of insulin resistance). BMI, total bilirubin, FFM, and GGT were found to have a positive relationship and homeostatic model assessment for insulin resistance, MCV, MCHC, fat percentage, total protein, and WHR were found to have a negative correlation to vitamin D concentration in response to supplementation. The accuracy of RF in predicting the response was 93% compared to logistic

show abstract

Nanofortification

Ghosh

Sikdar²,

Bandyopadhyay³

2022

Nanotechnology in Functional Foods

View full text Add to dashboard Cite

The efficacy of dairy products fortified with nano-encapsulated vitamin D3 on physical and mental aspects of the health in obese subjects; the protocol of the SUVINA trial

Cited by 8 publications

References 38 publications

Association of dietary and blood inflammatory indicators with depression, anxiety, and stress in adults with vitamin D deficiency

Association of dietary and blood inflammatory indicators with depression, anxiety, and stress in adults with vitamin D deficiency

Factors determining the serum 25‐hydroxyvitamin D response to vitamin D supplementation: Data mining approach

Nanofortification

Contact Info

Product

Resources

About