2021
DOI: 10.2147/ceg.s275985
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The Efficacy of Intraoperative Fluorescent Imaging Using Indocyanine Green for Cholangiography During Cholecystectomy and Hepatectomy

Abstract: Purpose Bile duct injury is one of the most serious complications of laparoscopic cholecystectomy. Intraoperative indocyanine green (ICG) cholangiography is a safe and useful navigation modality for confirming the biliary anatomy. ICG cholangiography is expected to be a routine method for helping avoid bile duct injuries. Patients and Methods We examined 25 patients who underwent intraoperative cholangiography using ICG fluorescence. Two methods of ICG injection are use… Show more

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Cited by 18 publications
(15 citation statements)
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“…Shibata et al described the differences between intravenous ICG administration versus intrabiliary administration with 12 patients in each group [ 16 ]. However, the ICG administration in the intrabiliary group was performed in three different ways: via transhepatic gallbladder drainage in 8 patients, through an endoscopic nasobiliary drainage in 1 patient, and by direct gallbladder injection in 3 patients.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Shibata et al described the differences between intravenous ICG administration versus intrabiliary administration with 12 patients in each group [ 16 ]. However, the ICG administration in the intrabiliary group was performed in three different ways: via transhepatic gallbladder drainage in 8 patients, through an endoscopic nasobiliary drainage in 1 patient, and by direct gallbladder injection in 3 patients.…”
Section: Discussionmentioning
confidence: 99%
“…Several authors have described the usefulness of performing intraoperative fluorescence cholangiography with intravenous ICG injection, demonstrating how it facilitates the surgeon’s task of correctly highlighting and recognizing vital biliary structures even before any dissection takes place [ 6 , 7 , 8 , 9 ]. The direct injection of ICG into the gallbladder has also been proposed to achieve fluorescence cholangiography, although evidence on this modality is still quite limited [ 10 , 11 , 12 , 13 , 14 , 15 , 16 ].…”
Section: Introductionmentioning
confidence: 99%
“…The usual routes of ICG administration include veins, 5,7 endoscopic nasobiliary drainage tube, 8 and the stump of the cystic duct 9 for fluorescence-guided surgery involving the hepato-biliary-pancreatic system. Among these routes, intravenous administration is convenient for LD of liver cysts because it does not require endoscopic nasobiliary drainage tube placement or cholecystectomy to expose and cut the cystic ducts.…”
Section: Discussionmentioning
confidence: 99%
“…ICG is often used to evaluate blood flow and perfusion of organs; however, medical insurance does not cover its use in cholangiography. Recently, use of ICG has been implemented with concurrent cholangiography following angiography during laparoscopic cholecystectomy and hepatectomy, after excretion into the biliary tract 5 . ICG fluorescent imaging provides at least three practical benefits, namely, 1 clear visualization of the biliary branches along the cyst wall, 2 easier recognition of the boundary between the thinned liver parenchyma and the cyst wall, and accurate detection of bile leakage from the cyst wall after the deroofing procedure 3 .…”
Section: Introductionmentioning
confidence: 99%
“…This team also preferred the use of a Veress needle and administration of 4 mL of 0.5 mg/mL ICG solution, while the entry point in the gallbladder was secured with a simple stitch[ 20 ]. Shibata et al [ 21 ] examined 24 patients who underwent LC under ICG fluorescence guidance, with half receiving intravenous ICG and the other half receiving intrabiliary injection. The latter was achieved either through PTGBD administration in 8 cases, or gallbladder puncture in 3 cases or administration through and endoscopic nasobiliary drainage (ENBD), which was placed in situ during previous ERCP, in one case and injection of a dosage of 0.025 mg[ 21 ].…”
Section: Icg Administration Technique and Dosagementioning
confidence: 99%