2017
DOI: 10.1016/j.vetpar.2017.08.019
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The efficacy of the supramolecular complexes of niclosamide obtained by mechanochemical technology and targeted delivery against cestode infection of animals

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Cited by 16 publications
(8 citation statements)
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“…Physicochemical properties and solid phase changes of obtained complexes were evaluated by methods of granulometric analysis, infrared spectral studies; thermal analysis; scanning electron microscopy; the analysis of solubility; and X-ray analysis. These methods were described previously in detail [8,22–24].…”
Section: Methodsmentioning
confidence: 99%
“…Physicochemical properties and solid phase changes of obtained complexes were evaluated by methods of granulometric analysis, infrared spectral studies; thermal analysis; scanning electron microscopy; the analysis of solubility; and X-ray analysis. These methods were described previously in detail [8,22–24].…”
Section: Methodsmentioning
confidence: 99%
“…Niclosamide (NS) is widely used for the treatment of cestode infection in animals, and to increase its solubility, it was done mechanochemical treated with PVP and obtained SD as a flowable beige powder [57]. Notable differences were observed with X-ray analysis in the SD of NS and PVP: it was established that a decrease of the intensity of the crystalline phase and disappearance of peaks (reflexes) of NS took place because of a disordering of the crystal structure and the formation of the SD in amorphous state ( Table 1).…”
Section: Solid Dispersions Of Anthelmintics For Animal Healthmentioning
confidence: 99%
“…Niclosamide (NS) is widely used to treat cestode infection of animals and for increasing its solubility was used its mechanochemical treatment with PVP and SD in the form of a flowing beige powder was taken [45] . Notable differences were observed with X-ray analysis in the SD of NS and PVP: it was established that a decrease of the intensity of the crystalline phase and disappearance of peaks (reflexes) of NS took place because of disordering of the crystal structure and the formation of the SD in amorphous state.…”
Section: Solid Dispersions Of Antiparasitic Drugs For Animal Healthmentioning
confidence: 99%