The efficiency of child formula dentifrices containing different calcium and phosphate compounds on artificial enamel caries

Rirattanapong, Praphasri; Vongsavan, Kadkao; Saengsirinavin, Chavengkiat; Khumsub, Ploychompoo

doi:10.4103/2231-0762.195517

Cited by 8 publications

(6 citation statements)

References 35 publications

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“…The role of SLS was also considered important for strong adherence to the enamel surface and for uptake of mineralizing ions to enamel surface. [ 41 ] The high remineralizing capacity of the BAG Novamin observed in the current study may be attributed to its high content of calcium and phosphate and at the micro level where BAG plug could be more compact and intimately attached to the enamel surface. SEM analysis done in one study showed that the deposits formed by BAG Novamin were larger, more angular as compared to other remineralizing agents which can be attributed to high microhardness.…”

Section: Discussionmentioning

confidence: 78%

Comparative evaluation of the remineralizing potential of commercially available agents on artificially demineralized human enamel: An In vitro study

et al. 2019

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Background: Caries is highly prevalent multifactorial disease, but its progression can be prevented in the initial stage of demineralization through remineralization (RML). Various materials have been proposed for the same, successful outcome can prove to be a boon in the prevention of caries. Aim: The aim of the study is to assess the RML potential of four commercially available agents so as to restore the enamel closest to its previous microhardness levels. Materials and Methods: Sixty permanent intact premolars were randomly divided into six groups: Four test groups – (1) bioactive glass (BAG) Novamin (SHY-NM), (2) nano-hydroxyapatite (nHAp) (Acclaim), (3) functionalized tricalcium phosphate (f-TCP) (Clinpro Tooth Crème), and (4) grape seed extract (GSE); one positive control – (5) fluoride (1000 ppm) containing dentifrice (Colgate Calci-Lock); and one negative control – (6) distilled water. The samples were initially evaluated for baseline surface microhardness (SMH); later on, these samples were placed in the demineralizing solution for 48 h in an incubator at 37°C, and postdemineralization again SMH was measured. Thereafter, the samples were subjected to the pH cycling for consecutive 21 days, and SMH was recorded. The SMH was evaluated using a Vickers microhardness tester. Statistical analysis was done using a post hoc Tukey test for each group based on the stage of treatment and one-way ANOVA for comparison among different groups. Results: BAG Novamin showed SMH recovery at 96.75% followed by f-TCP at 95.83%, nHAp at 90.88%, and GSE at 48.71%. Statistically significant differences were observed between the first three groups and the rest of the groups after RML stage. Conclusion: BAG Novamin, f-TCP, and nHAp showed considerable RML followed to a lesser extent by GSE.

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Section: Discussionmentioning

confidence: 78%

Comparative evaluation of the remineralizing potential of commercially available agents on artificially demineralized human enamel: An In vitro study

et al. 2019

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“…Demineralization occurs when the pH of the oral environment drops below 5.5, allowing calcium and phosphate ions to diffuse from the enamel surface (Shen et al, 2015;Abou Neel et al, 2016). The duration and frequency of acid challenge can affect the level of damage to the tooth structure, which can range from small white spots to cavitation (Rirattanapong et al, 2017). It should be emphasized that when the enamel surface remains partially intact, there is an opportunity to stop carious lesions by the joint action of saliva minerals and fluoride therapy (Vanichvatana & Auychai, 2013;Farooq & Bugshan, 2020).…”

Section: Discussionmentioning

confidence: 99%

“…Toothpaste with fluoride can be more effective for enhancing remineralization, if tricalcium phosphate is added to it. It has been established that this agent delays the interaction of calcium with ionic fluoride, which allows more fluoride and calcium ions to be delivered to the demineralized enamel (Vanicvatana & Auychai, 2013;Rirattanapong et al, 2017). It should be noted that although fluoride ions are adsorbed on the surface of enamel crystals, preventing dissolution and enhancing remineralization, demineralized surface lesions remineralize faster and more fully than subsurface lesions.…”

Section: Discussionmentioning

confidence: 99%

Morphological structure of enamel caries in the dynamic process of demineralization and remineralization

Gevkaliuk,

Nazarenko

2023

Regul. Mech. Biosyst.

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According to modern ideas, the carious process at the white spot stage is reversible, so all the attention of scientists is directed to the development of means to restore the crystal lattice of tooth enamel. The purpose of the study is to evaluate morphological changes in caries at the white spot stage and the process of structural remineralization of the carious lesion area. Clinically active initial lesions were detected visually, using optical magnification and positive staining. Structural changes in enamel were studied by scanning electron microscopy of surface impressions obtained from the surface of demineralized enamel. Remineralizing therapy was carried out by applying ApaCare restorative gel (Germany) with nanodispersed highly active hydroxyapatite. Determination of the intensity of dental caries by the DMFT and dmft index showed 9.04 ± 0.40 points on average in the group of subjects, children with code 1 according to the ICDAS index made up 50.8%. Colour reactions showed 7.80 ± 0.21 points on average in the group. SEM visualized characteristic structural changes in the area of the carious spot – an increase in the porosity of the enamel surface with exposure of the fine crystalline structure and destruction of interprismatic fibrillar structures. When using a remineralizing agent, a roller-like deposition of an amorphous remineralizing substance is characteristic, and at the final stage, a smooth enamel surface with a fine crystal lattice is restored. The restoration of the prismatic structure of the enamel occurs due to the mineralization of the preserved fibrillar walls in the interprismatic space. Clinically, at this stage, the enamel visually restores its original shine, smoothness, and colour. In 81.8% of cases, the dye did not penetrate the previously demineralized enamel. The high level of non-cavitated active caries lesions can be largely controlled by the use of remineralizing agents. Further research involves studying the quantitative characteristics of the processes of de- and remineralization of tooth enamel.

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“…In some studies, CPP-ACP has shown superior efficacy to fluoride in caries management (38,39). By contrast, in 2016 Rirattanapong et al (47) reported that 500 ppm F toothpaste had a superior remineralization efficiency than CPP-APP.…”

Section: Discussionmentioning

confidence: 99%

Effect of Different Remineralization Agents on Artificial Caries Lesion: An in-vitro Study

AKBEYAZ ŞİVET,

PARLAKYILDIZ GÖKÇE,

KARGUL

2023

Clinical and Experimental Health Sciences

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Objective: Remineralization technologies have been shown to arrest or reverse early carious lesions. This study aimed to evaluate and compare the effect of different agents on enamel remineralization in-vitro. Methods: Thirty-five enamel blocks were prepared and divided into the following groups: Group 1; CaGp and Xylitol-containing gel (R.O.C.S Medical Mineral Gel), Group 2; 1100 ppm NaF and 10% CPP-ACP toothpaste (MI Paste One), Group 3; 0.45% SnF2-1150 ppm F toothpaste (Enamelon), Group 4; Positive Control-1450 ppm NaF toothpaste (Colgate Total) and Group 5; Negative Control (deionized water). Microhardness was measured at baseline, after demineralization, and after respective treatments for different treatment groups using a digital Micro Vickers Hardness Tester. For producing demineralized lesions, samples were stored in acidic hydroxyethylcellulose (HEC, pH=4.8) for three days. The Paired Sample t-test, one-way ANOVA, and Tukey were used to compare data and SMH recovery (%SMHR) calculated among treatments. Results: The mean baseline surface microhardness value was statistically non-significant between the groups (p=.378). CaGP and Xylitolcontaining gel demonstrated having the most protective effect against demineralization. The surface remineralization potential of 1100 ppm NaF and 10% CPP-ACP containing novel toothpaste (MI Paste One) was almost similar to the positive control (1450 ppm Fluoride toothpaste)group (p>.05). Conclusions: All treatment groups showed remineralization after respective treatments and these agents can be used as an effective preventive measure for pediatric patients.

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The efficiency of child formula dentifrices containing different calcium and phosphate compounds on artificial enamel caries

Cited by 8 publications

References 35 publications

Comparative evaluation of the remineralizing potential of commercially available agents on artificially demineralized human enamel: An In vitro study

Comparative evaluation of the remineralizing potential of commercially available agents on artificially demineralized human enamel: An In vitro study

Morphological structure of enamel caries in the dynamic process of demineralization and remineralization

Effect of Different Remineralization Agents on Artificial Caries Lesion: An in-vitro Study

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