The Efficiency of Synthetic Sex Pheromones in Sexual Arousal Stimulation in Domestic Dogs

Dzięcioł, Michał; Niżański, Wojciech; Jezierski, Tadeusz; Szumny, Antoni; Godzińska, Ewa Joanna; Ochota, Małgorzata; Stańczyk, Ewa; Najder-Kozdrowska, Lidia; Woszczyło, Martyna; Pieczewska, Barbara

doi:10.1515/pjvs-2017-0052

Cited by 14 publications

(23 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Alimentary lymphoma can appear with different features in the GI tract: It can occur as a focal or multifocal hypoechoic intestinal mass with transmural loss of wall layering, causing partial stenosis of the intestinal lumen or it may appear as a normal or increased intestinal wall thickness with preservation of intestinal layers (Penninck, 1998;Lingard et al, 2009;Gieger, 2011;Gaschen, 2011). Furthermore, it is the most common neoplastic cause of diffuse infiltration and wall thickening in cats that can appear similar to Inflammatory Bowel Disease (IBD) (Gaschen, 2011;Gianella et al, 2017). In cats, AL, as previously told, is the most commonly encountered form of lymphoma and the three main histological types, LGAL, HGAL and LGLL, have different diffusion, aggressiveness and prognosis.…”

Section: Intestinementioning

confidence: 99%

“…Clinical signs depend on which portion of the GI tract is involved and usually include chronic vomiting and/or diarrhea, gastro-intestinal blood loss (hematemesis, melena and/or hematochezia) with weight loss that could result from anorexia, malabsorption and/or maldigestion, loss of protein or generalized tumour cachexia. Laboratory abnormalities may include panhypoproteinemia, microcytic hypochromic anemia related to chronic gastro-intestinal blood loss and malabsorption (Willard, 2012;Terragni et al, 2014b;Gianella et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Diagnostic Imaging of Gastrointestinal Tumours in Dogs and Cats: A Review

Simeoni¹,

Signore²,

Terragni³

et al. 2020

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

Gastrointestinal tract tumours in dogs and cats are characterized by non-specific clinical presentation and laboratory abnormalities, but require fast identification, characterization and staging. Imaging techniques play a key role in the diagnostic process of these diseases in routine veterinary practice. Survey and contrast radiography may indicate primary or secondary signs of gastric or intestinal neoplasia such as a wall mass, functional alterations and stenosis points, but they have low sensibility and limited diagnostic value. Ultrasound allows to perform a detailed study of gastrointestinal wall's layers and thickness and adjacent organs but requires adequate acoustic windows and expert operators. Computed tomography is a reference technique both in human and veterinary oncology for the identification of primary neoplasms and for metastases searching thanks to the possibility to scan the whole body and the use of intravenous iodinated contrast medium for vascular assessment. Specific intraluminal distension techniques such as Helical-Hydro Computed Tomography and Computed Tomography Colonography can improve respectively stomach and colon associated masses. To date, Endoscopic Ultrasonography and Magnetic Resonance, despite their proven value in human medicine, lack of literatures that support their usefulness in the diagnosis and staging of gastrointestinal neoplasms in veterinary medicine and are not widely used in these pathologies. The purpose of this work is to review the literature on imaging modalities applied in gastrointestinal tumours diagnosis in dogs and cats, highlighting advantages and limitations of each technique in order to choose the proper imaging procedure in everyday clinical practice.

show abstract

Section: Intestinementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Diagnostic Imaging of Gastrointestinal Tumours in Dogs and Cats: A Review

Simeoni¹,

Signore²,

Terragni³

et al. 2020

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

show abstract

“…As mentioned above, the clinical signs of LGAL are not pathognomonic making diagnosis challenging. During diagnostic investigations, metabolic diseases, endocrinopathies, infectious diseases, chronic cholangitis, pancreatitis, and exocrine pancreatic insufficiency should first be ruled out using clinicopathological testing and diagnostic imaging [ 79 , 82 ]. Thereafter, LGAL should be differentiated from other gastrointestinal tract diseases such as food-responsive enteropathy (FRE) and IBD.…”

Section: Diagnosismentioning

confidence: 99%

“…To the authors’ knowledge, no study has yet demonstrated the ability of paraclinical data to differentiate LGAL from IBD. However, failure to recognise and correct hypocobalaminaemia is known to delay clinical recovery, even when specific therapy for AL or IBD is instituted [ 82 , 86 ]. Hypoalbuminaemia is reported in 70% of cats with AL, 49% with LGAL, and 77% with IBD respectively [ 20 , 87 ].…”

Section: Diagnosismentioning

confidence: 99%

“…In dogs, cytokine IL6 suppresses albumin synthesis and may be released by neoplastic cells [ 88 ], and this might contribute to the progressive hypoalbuminaemia observed in AL [ 88 , 89 ]. Previous studies have documented the prevalence of hypocobalaminaemia in cats with gastrointestinal disease, with approximately a third of IBD cases being affected [ 82 , 83 , 87 , 90 – 93 ]. Between 50 and 80% of LGAL are associated with hypocobalaminaemia (Ref.…”

Section: Diagnosismentioning

confidence: 99%

See 1 more Smart Citation

Feline low-grade alimentary lymphoma: an emerging entity and a potential animal model for human disease

et al. 2018

View full text Add to dashboard Cite

BackgroundLow-grade alimentary lymphoma (LGAL) is characterised by the infiltration of neoplastic T-lymphocytes, typically in the small intestine. The incidence of LGAL has increased over the last ten years and it is now the most frequent digestive neoplasia in cats and comprises 60 to 75% of gastrointestinal lymphoma cases. Given that LGAL shares common clinical, paraclinical and ultrasonographic features with inflammatory bowel diseases, establishing a diagnosis is challenging. A review was designed to summarise current knowledge of the pathogenesis, diagnosis, prognosis and treatment of feline LGAL. Electronic searches of PubMed and Science Direct were carried out without date or language restrictions.ResultsA total of 176 peer-reviewed documents were identified and most of which were published in the last twenty years. 130 studies were found from the veterinary literature and 46 from the human medicine literature. Heterogeneity of study designs and outcome measures made meta-analysis inappropriate. The pathophysiology of feline LGAL still needs to be elucidated, not least the putative roles of infectious agents, environmental factors as well as genetic events. The most common therapeutic strategy is combination treatment with prednisolone and chlorambucil, and prolonged remission can often be achieved. Developments in immunohistochemical analysis and clonality testing have improved the confidence of clinicians in obtaining a correct diagnosis between LGAL and IBD. The condition shares similarities with some diseases in humans, especially human indolent T-cell lymphoproliferative disorder of the gastrointestinal tract.ConclusionsThe pathophysiology of feline LGAL still needs to be elucidated and prospective studies as well as standardisation of therapeutic strategies are needed. A combination of conventional histopathology and immunohistochemistry remains the current gold-standard test, but clinicians should be cautious about reclassifying cats previously diagnosed with IBD to lymphoma on the basis of clonality testing. Importantly, feline LGAL could be considered to be a potential animal model for indolent digestive T-cell lymphoproliferative disorder, a rare condition in human medicine.

show abstract