The elderly patient with chronic kidney disease

Hansberry, Maria R.; Whittier, William L.; Krause, Michelle W.

doi:10.1053/j.ackd.2004.10.013

Cited by 27 publications

(21 citation statements)

References 52 publications

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“…Also elderly population is susceptible to kidney damage from other chronic diseases such as hypertension, diabetes mellitus, and tubulointerstitial disorders [6]. So early diagnosis and implementation of therapeutic strategies have been emphasized to delay the progression of disease and increase quality of life in these patients [7]. …”

Section: Introductionmentioning

confidence: 99%

Prevalence of Chronic Kidney Disease and Its Related Risk Factors in Elderly of Southern Iran: A Population-Based Study

et al. 2013

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Aim. The prevalence of chronic kidney disease (CKD) as a serious public health problem is growing in the elderly. This study aimed to assess CKD prevalence and its related risk factors in elderly population of Fars province. Methods. In this cross sectional study a total of 1190 elderly people are enrolled, and demographic and medical data were obtained. Data were analyzed by SPSS, and P of less than 0.05 was considered as statistically significant. Results. Prevalence of CKD stages III–V was 27.5% in the 60–69 years age group, 36.5% in the 70–79 years age group, and 40% in the ≥80 years age group. The prevalence of CKD increased with ageing in both men and women. Female gender was the strongest risk factor for CKD. Conclusions. Prevalence of CKD in elderly is high in Southern Iran, which has become an important health problem while it can be prevented or delayed in progression.

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Section: Introductionmentioning

confidence: 99%

Prevalence of Chronic Kidney Disease and Its Related Risk Factors in Elderly of Southern Iran: A Population-Based Study

et al. 2013

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“…In other studies, the elderly had a markedly higher prevalence of CKD, and the prevalence increased with age in all populations, particularly among elderly persons aged 70 years or older. [10,21,[31][32][33] Concerning …”

Section: Estimating Equations Of Egfrmentioning

confidence: 99%

“…The survey covered 31,999 people across Tehran (in a population of 12 million) during the study period. The mean and SD of age of participants was 43.77 ± 11.32 (range from18 to 86) years, and 98.4% (31,489) were male. Using the MDRD equation, overall prevalence of eGFR <60 mL/min/1.73 m 2 was 6.5%.…”

mentioning

confidence: 99%

Screening for Decreased Renal Function in Taxi Drivers in Tehran, Iran

Mahdavi‐Mazdeh

Nazri

Hajghasemi³

et al. 2010

Renal Failure

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Background and objectives. The rapid increase in end stage renal disease (ESRD) prevalence, plus the enormous cost of treatment, necessitates an urgent approach to implement strategies to prevent development and progression of ESRD, especially in the developing world. Screening that leads to early identification and treatment has been recommended, as it may slow or prevent progression to a more expensive and disabling stage of the disease and thus may save lives as well as finite resources. Methods. In 2007, the Healthy City Office of Tehran municipality conducted a large-scale population-based crosssectional survey titled "Kidney Disease Screening of Taxi Drivers in Tehran." Taxi drivers or applicants of purchasing taxi participated in mentioned screening program in the last three months of 2007. Demographic data, blood pressure, and history of hypertension or smoking-and then in specific laboratories creatinine, lipid profile, complete blood count, fasting blood sugar, and urinalysis-have been checked. Results. The survey covered 31,999 people across Tehran (in a population of 12 million) during the study period. The mean and SD of age of participants was 43.77 ± 11.32 (range from18 to 86) years, and 98.4% (31,489) were male. Using the MDRD equation, overall prevalence of eGFR <60 mL/min/1.73 m 2 was 6.5%. However, the prevalence was 6.4% (1982/30949) in males in relation to 13.7% (69/503) in females. Mean and SD of BMI in males and females were 25.90 ± 3.91 and 26.48 ± 4.50 g, respectively. The overall prevalence of proteinuria (≥1+ proteinuria) was 0.6% in males vs. 1.8% in females in normal GFR group. Age, LDL cholesterol, hypertension, blood glucose, and BMI showed to be strong risk factors for low GFR. Education level did not show a significant correlation with low GFR. Discussion and conclusions. The findings of the study insist on the fact that CKD prevalence is significantly higher in old age, females, hypertensives, and uncontrolled diabetic patients. Our ability to decrease the incidence of ESRD is predicated on recognizing those patients with CKD and implementing all preventive strategies.

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“…The average age of patients starting dialysis has been increasing [2]. These patients often consider prognosis while making these decisions [1,3].…”

Section: Introductionmentioning

confidence: 99%

What are the Risk Factors for One-Year Mortality in Older Patients with Chronic Kidney Disease? An Analysis of the Cleveland Clinic CKD Registry

Saeed

Arrigain

Schold

et al. 2018

Nephron

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Background: Prognostic factors after dialysis initiation among older chronic kidney disease (CKD) patients are not well studied. In this study, we examined the risk factors associated with 1-year mortality after dialysis initiation among older CKD patients. Methods: In this retrospective study, we included 621 CKD patients from an electronic medical record based CKD registry that was linked to the United States Renal Data System data. In terms of age, they were all ≥65. We examined the associations of various demographic factors, comorbid conditions, relevant laboratory parameters, the presence of arteriovenous fistula, and inability to take care of oneself with 1-year mortality after dialysis initiation using Cox proportional hazards model. Results: In our study cohort, 224 older patients died during the first year of dialysis initiation and the estimated survival at 1 year was 65% (95% CI 62–69). After adjusting for covariates, increasing age by each year (Hazard ratio 1.04 [95% CI 1.02–1.06]), congestive heart failure (CHF; 1.57 [1.13–2.18]), an absence of AVF (3.0 [1.7–5.1]) and lack of nephrology care prior to dialysis initiation (1.93 [1.39–2.70]) were associated with increased risk of 1-year mortality. Nearly 60% of deaths were due to non-cardiovascular (CV) causes including cancer. Conclusion: Risk factors portending high 1-year mortality in older CKD patients are increasing age, CHF, an absence of AVF, and lack of pre-dialysis nephrology care. Clinicians need to be aware of non-CV risks of high mortality in these patients.

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The elderly patient with chronic kidney disease

Cited by 27 publications

References 52 publications

Prevalence of Chronic Kidney Disease and Its Related Risk Factors in Elderly of Southern Iran: A Population-Based Study

Prevalence of Chronic Kidney Disease and Its Related Risk Factors in Elderly of Southern Iran: A Population-Based Study

Screening for Decreased Renal Function in Taxi Drivers in Tehran, Iran

What are the Risk Factors for One-Year Mortality in Older Patients with Chronic Kidney Disease? An Analysis of the Cleveland Clinic CKD Registry

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