The Electrical Activities of Single Motoneurones in Toad's Spinal Cord, Recorded With Intracellular Electrodes

Araki, T.; Otani, Takuzo; Furukawa, Taro

doi:10.2170/jjphysiol.3.254

Cited by 58 publications

(25 citation statements)

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“…The positive after-potential was similar in time course to the after-hyperpolarization of amphibian motoneurons, and both kinds of potentials depress excitatory processes elicited during this period (ARAKI, OTANI & FURUKAWA, 1953). In addition, the positive after-potentials may be similar to the after-hyperpolarization in the point that they occurred only of ter the propagated spikes (ECCLES, 1957).…”

Section: Discussionmentioning

confidence: 85%

Abortive Spikes of the Frog Muscle Spindle

Ito

1969

Jpn.J.Physiol

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Section: Discussionmentioning

confidence: 85%

Abortive Spikes of the Frog Muscle Spindle

Ito

1969

Jpn.J.Physiol

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“…followed by a series of two or three delayed e.p.s.p.s (cf. Araki, Otani & Furukawa, 1953;Machne, Fadiga & Brookhart, 1959;Katz & Miledi, 1963). In contrast to the short latency e.p.s.p., the delayed components of the dorsal root e.p.s.p.…”

Section: Discussionmentioning

confidence: 90%

Effects of some divalent cations on synaptic transmission in frog spinal neurones.

Álvarez-Leefmans¹,

Santis²,

Miledi³

1979

The Journal of Physiology

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SUMMARY1. Synaptic transmission between dorsal root afferents and motoneurones was studied in the isolated and hemisected spinal cord of frogs, using intracellular and extracellular recording techniques, and ionic substitutions of divalent cations in the bathing fluid.2. Delayed components of excitatory post-synaptic potentials (e.p.s.p.s) evoked in motoneurones by dorsal root supramaximal stimuli, as well as the Ca2+-dependent slow after-hyperpolarization which follows antidromic spikes, were reversibly blocked by superfusing the cords with 'Ca2+-free' media containing C02+ (4 mM) or Mg2+

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“…This view was further developed in a later article (Brock et al, 1953) in which an attempt was also made to justify the difference of depolarization level required for initiation of soma firing following orthodromic or antidromic stimulation. Araki, Otani, and Furukawa (1953) working with toads noted that an inflection is often present also in the rising phase of orthodromically evoked spikes, and Araki and Otani (1955) recorded a similar inflection also in spikes evoked by direct stimulation of toad's motoneurons. They interpreted these findings by assuming that " .…”

mentioning

confidence: 94%

Steps in the Production of Motoneuron Spikes

Fuortes

Frank

Becker

1957

The Journal of General Physiology

303

147

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The first report on action potentials recorded with intracellular electrodes from motoneurons (Brock, Coombs, and Eccles, 1951) described orthodromic and antidromic spikes as identical except for presence of a synaptic potential at the foot of the spike evoked by orthodromic stimulation. It was later recognized (Brock et al., 1952 a and b) that a difference exists in the rising phase of spikes evoked by orthodromic or antidromic stimulation, and it was stated that antidromic spikes show an initial fast rise of about 35 mv., an inflection, and a further fast rise to peak, while the orthodromic spikes present an initial slow rise of about 10 mv. (the synaptic potential) an inflection there, and a further fast and smooth rise to peak. It was then suggested that " . . . the spike response of the neurone began at the inflection on the rising phase . . . . In the former [antidromic] the inflection indicates origin of the neuronal spike from the spike of the non-medullated axon, in the latter [orthodromic] its origin from the synaptic potential" (Brock el al., 1952 a, p. 440). This view was further developed in a later article (Brock et al., 1953) in which an attempt was also made to justify the difference of depolarization level required for initiation of soma firing following orthodromic or antidromic stimulation. Araki, Otani, and Furukawa (1953) working with toads noted that an inflection is often present also in the rising phase of orthodromically evoked spikes, and Araki and Otani (1955) recorded a similar inflection also in spikes evoked by direct stimulation of toad's motoneurons. They interpreted these findings by assuming that " . . . the non-myelinated segment is more excitable than the soma, so that the local current due to synaptic potential may excite it primarily, as suggested by Gesell" (Araki and Otani, 1955, p. 475). Frank and Fuortes (1955 b) confirmed the presence of an inflection in the rising phase of orthodromic spikes and showed in addition that orthodromically evoked spikes may be made to fall from the point of inflection just as occurs for antidromic

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The Electrical Activities of Single Motoneurones in Toad's Spinal Cord, Recorded With Intracellular Electrodes

Abstract: The technique of recording electrical activities of single cells by means of intracellular micro-electrodes was first developed by Curtis and Cole (5) and Recently Brock, Coombs and Eccles (4) reported an ingeneous investigation

Cited by 58 publications

References 6 publications

Abortive Spikes of the Frog Muscle Spindle

Abortive Spikes of the Frog Muscle Spindle

Effects of some divalent cations on synaptic transmission in frog spinal neurones.

Steps in the Production of Motoneuron Spikes

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