The Electrochemical Detection of Penicillins in Milk

Toxic Compounds Analysis With High Performance Liquid Chromatography Detected By Electro Chemical Detector (Ecd)

“…A number of penicillin antibiotics, including amoxicillin, ampicillin, cloxacillin and penicillin G (benzylpenicillin) have been measured in milk using a C18-modified silica column with gradient elution (acetonitrile-methano1-aqueous acetate buffer (20 mmoI L -1 ) and PAD (pulsed amperometric detection, serial dua1 Au electrodes, Ag/AgCI reference) [20]. Sample preparation was by preconcentration of the analytes on the analytical column af-ter protein precipitation with acetonitrile and fat extraction using dichloromethane-hexane (1/1.…”

Determination of penicillins in animal tissues at trace residue concentrations: II. determination of amoxicillin and ampicillin in liver and muscle using cation exchange and porous graphitic carbon solid phase extraction and high‐performance liquid chromatography

“…Moats (1994) carried out the analysis of both amoxicillin and ampicillin in milk using HPLC fractionation for clean-up following an ionpair extraction method. Kirchmann et al (1994) used direct and indirect pulsed amperometric electrochemical detection for the determination of penicillins including amoxicillin and ampicillin in milk. There are even fewer methods for the analysis of ampicillin or amoxicillin in other tissues.…”