The Electrocyclization of Heptatrienyl Anions

Abstract

The thermal electrocyclization of heptatrienyl anions is reviewed. We begin with a succinct background on the importance of cycloheptane rings in complex molecules and a brief survey of approaches to their synthesis. We also review the fundamental aspects of this electrocyclization manifold, relying on the Woodward–Hoffmann rules for pericyclic chemistry. Then we survey the literature, covering the burst of discovery in the late 1960s and early 1970s, and the more sporadic reports in from the 1990s to the present day.1 Introduction2 The Electrocyclization of Heptatrienyl Anions3 Discovery and Early Development (1964–1975)4 Recent Developments (1996–2023)5 Concluding Remarks

Cyсlopentadienone and Pyrone Derivatives as Precursors of Electron-Deficient Cycloheptatrienes: Quantum Chemical Investigation and Synthesis

“…1,[6][7][8][9][10] There are only several general methods for the synthesis of such cycloheptatrienes. Previously, we have extensively investigated [11][12][13][14] the scope of the cascade assemble of electron-defficient cycloheptatriene derivatives from simple molecules with an electrocyclic ring-closure 15,16 at the late stages. Classical Büchner approach [17][18][19][20][21] is hardly applicable to the synthesis of cycloheptatrienes with more than one electron-withdrawing group.…”