The Electroencephalogram in Congenital Hypothyroidism: A Study of 10 Cases

Nieman, E. A.

doi:10.1136/jnnp.24.1.50

Cited by 15 publications

(8 citation statements)

References 5 publications

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“…Slow activity and low voltage were described by most workers (19,21,27,31). Some workers reported the presence of unusually mature tracings (27), while others described the presence of discharges of fast activity and spikes (31). A positive correlation between the severity of mental retardation and the degree of electroencephalographic abnormalities has been postulated (18,19,22).…”

mentioning

confidence: 89%

“…These studies were usually performed on previously treated cretins with few cases being followed. Slow activity and low voltage were described by most workers (19,21,27,31). Some workers reported the presence of unusually mature tracings (27), while others described the presence of discharges of fast activity and spikes (31).…”

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confidence: 93%

“…Electroencephalography is the only practical method for assessing functional cerebral activity in living persons (29), relatively. A fairly large number of reports on electroencephalographic changes in hypothyroidism h a v e bee n published (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31). Most of these reports were concerned with adult cases of myxoedema.…”

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confidence: 94%

“…A positive correlation between the severity of mental retardation and the degree of electroencephalographic abnormalities has been postulated (18,19,22). Nieman, (27) however, cautions that before this can be accepted more cases should be carefully followed. A review of the literature leads us to conclude that one more study, particularly one that was broadly medical rather than narrowly electroencephalographic, might help to clarify the subject.…”

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confidence: 97%

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Electro-Encephalographic Changes in Cretinism

Taher

Gabr

Shahin

et al. 1970

Clinical Electroencephalography

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confidence: 89%

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confidence: 93%

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confidence: 94%

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confidence: 97%

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Electro-Encephalographic Changes in Cretinism

Taher

Gabr

Shahin

et al. 1970

Clinical Electroencephalography

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“…It has been shown that (a) a-rhythm frequency and blood levels of thyroxin (T4) are positively correlated (13,14); (b) significant relationships exist between a-rhythm frequency and metabolic rate (15); and (c) a-rhythm increases after replacement therapy (16). On the other hand, no significant changes in a-rhythm frequency have been reported in either normals receiving 300 ^g T3 (17) or in hyperthyroid patients compared with normals (4, 18).…”

Section: Alpha Rhythm Frequencymentioning

confidence: 99%

Influence of Triiodothyronine on Selective Attention in Man as Measured by the Visual Averaged Evoked Potential

Lunde

et al. 1970

Psychosomatic Medicine

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Man is continually bombarded by stimuli. Some contain important information while others do not. By processing some stimuli and filtering out others, man selectively attends to his environment. It is possible to obtain an objective measure of attention directed toward a specific stimulus by measuring the averaged evoked potential (AEP) produced by that stimulus. The amplitude of the AEP is greater when the subject attends to a stimulus than when he ignores it while attending to the competing stimulus. The difference between these amplitudes is a measure of selective attention. Using this measure, we compared the effects of the thyroid hormone triiodothyronine (T3) with the effects of a placebo on normal subjects. T3 increased the amplitude of the AEP when the subject ignored the stimulus but had no effect on the amplitude when the subject attended to the stimulus. T3, therefore, reduced selective attention. This reduction of selective attention may explain some of the psychopathology observed in hyperthyroidism.The complex relationship between behavior and thyroid function, aspects of which were recently reviewed by Hamburg and Lunde (1), has been the concern of clinicians for almost 100 years (2). Clinically, the behavior of the hyperthyroid patient is often characterized by hyperexcitability, irritability, restlessness and exaggerated responses to environmental stimuli (3). Because these symptoms suggest alterations in perceptual mechanisms, several authors

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